About Pan-D Capsule 15’s
Pan-D Capsule 15’s is composed of two medicines, namely: Domperidone and Pantoprazole. Domperidone is a prokinetic and anti-nausea agent that helps to treat indigestion and stomach pain. On the other hand, Pantoprazole is a proton pump inhibitor that reduces the excess stomach acid formation by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). PanD Capsule 15’s is a widely used medicine to treat peptic ulcers and gastroesophageal reflux disease (GERD). Pan-D Capsule 15’s prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.
Domperidone works by increasing the movement of food through the stomach and the digestive tract more quickly and in this way reduces the feeling of bloating, or fullness and indigestion. On the other hand, it effectively blocks the action of a vomiting centre (chemoreceptor trigger zone – CTZ) located in your brain, that is responsible for inducing the feeling of nausea and vomiting. Pantoprazole helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum.
Pan-D Capsule 15’s can be prescribed to the adults and children aged 12 years and over. It is better to take Pan-D Capsule 15’s an hour before a meal. Pan-D Capsule 15’s should be swallowed whole with a glass of water. Do not chew, crush, or break it. Avoid intake of Pan-D Capsule 15’s for more than four weeks of duration without consulting the doctor. You can increase the efficacy of PanD Capsule 15’s by taking a small meal or snacks frequently. Try to avoid caffeine-containing beverages (coffee, tea), spicy/deep fried/processed foods, carbonated drinks, acidic foods like citrus fruits/vegetables (tomatoes).
Like all medicines, Pan-D Capsule 15’s may cause side effects, although not everybody gets them. The most common side effects of Pan-D Capsule 15’s are diarrhoea, stomach pain, flatulence (gas), dryness in the mouth, dizziness, and headache. Everyone doesn’t need to experience the above side effects. In case of any discomfort, speak with your doctor. Prolonged intake of Pantoprazole is associated with a low level of Vitamin B12 and low magnesium. Hence yearly test of Vitamin B12 and magnesium is required if you are taking PanD Capsule 15’s for the long term. Use of Pan-D Capsule 15’s is contraindicated in people with lupus (autoimmune inflammatory disease).
Uses of Pan-D Capsule 15’s
Gastroesophageal reflux disease (GERD), Heartburn due to hyperacidity, Inflammation of food pipe (esophagitis), Peptic ulcer
Pan-D Capsule 15’s plays a vital role in preventing nausea, vomiting, stomach upset, stomach pain, peptic ulcer, and other conditions due to hyperacidity or acid reflux. Pantoprazole prevents proton pumps gate from producing an excessive amount of stomach acid. While Domperidone stops nausea (feeling sick) and vomiting (being sick) blocking messages between parts of your brain called the chemoreceptor trigger zone (CTZ) and the vomiting center.
Directions for Use
Side Effects of Pan-D Capsule 15’s
Most of the side effects of PanD Capsule 15’s do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor. Some common side effects of Pan-D Capsule 15’s headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). Very rarely, it may cause swelling of the tongue and/or throat, difficulty in swallowing, difficulties in breathing, allergic facial swelling, severe dizziness with a very fast heartbeat, and heavy sweating. blistering of the skin, acute kidney injury, yellowing of the skin, fever, rash, and enlarged kidneys sometimes with painful urination, and lower back pain (serious inflammation of the kidneys), possibly leading to kidney failure. This requires immediate medical attention.
In-Depth Precautions and Warning
You should avoid taking Pan-D Capsule 15’s if you are allergic to Pan-D Capsule 15’s or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. Pan-D Capsule 15’s may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Pan-D Capsule 15’s may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Pan-D Capsule 15’s may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor.
Drug-Drug Interaction: Pan-D Capsule 15’s may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, posaconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, antibiotic (ampicillin, rifampicin), heart medicine (digoxin) and anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines.
Drug-Food Interaction: PanD Capsule 15’s interact with St John’s wort plant that is used as an anti-depressant. This plant may affect the working of Pan-D Capsule 15’s. So avoid its intake with Pan-D Capsule 15’s.
Drug-Disease Interaction: PanD Capsule 15’s should be not given in patients with C. difficile induced colitis, liver disease, bone fractures, low Vitamin B12 (anaemia), low magnesium (hypomagnesemia).