Nicostar 10 Tablet (Nicorandil)

Nicostar 10 Tablet

Nicostar 10Mg Tablet is a vasodilatory drug. It treats angina chest pain. This medication widens blood vessels thus increasing the blood and oxygen flow to the heart. This medication is used to treat other heart conditions also.

On using Nicostar 10Mg Tablet you may experience side effects such as rapid or irregular heartbeat, swelling, darkening of urine, dizziness, headache, nausea, fatigue, a decrease in blood pressure levels, flushes, skin rash, high potassium levels, muscle pain or stomach pain. Notify your physician if you face any of these effects.

Before using this medication tell your doctor if you are allergic to any of the ingredients contained within Nicostar 10Mg Tablet, having any other allergies, already taking any medications, have low blood pressure, skin/ mouth ulcers, heart problems or pulmonary oedema, are pregnant or are breastfeeding a baby.

The dosage should be prescribed by your doctor based on your medical history and current condition. The usual dose in adults is about 10 mg twice a day which may be increased to 20 mg depending on your response.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Cardiologist before using this medicine.

Use

The medicine is useful against the following conditions:

Chest Pain

Dosage

Nicostar 10 Tablet
Nicostar 5 Tablet
Nicostar OD 10 Tablet

Side Effects

Following are some of the common side effects that may occur:

Nausea

Vomiting

Headache

Weakness

Dizziness

Flushing

Dosage

Are there any missed dose instructions?

If you miss a dose of Nicorandil, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Work

This medication works following the dual mechanism. Firstly, it activates the ATP sensitive potassium channel, leading to vascular smooth muscle hyperpolarization. Secondly, it triggers guanylate cyclase to enhance the production of cyclic GMP, thereby activating protein kinase G. Therefore, GTPase RhoA is inhibited and Rho-kinase activity is decreased. As a result, the myosin phosphatase activity is accelerated and the calcium sensitivity of the smooth muscle is reduced. Owing to its nitrate property, nicorandil works as a vasodilator.