Tazloc Trio 80 Tablet (Telmisartan/Amlodipine/Hydrochlorothiazide)

Tazloc Trio 80 Tablet (Telmisartan/Amlodipine/Hydrochlorothiazide)

Tazloc Trio 80 Tablet is a combination medicine used for the treatment of high blood pressure. This medicine is not recommended for use in patients below 18 years of age. It is also not recommended as initial therapy for high blood pressure. Patients are advised to maintain a strict exercise and diet regimen along with this medicine for the best possible effect.

Side effects

Major & minor side effects for Tazloc Trio 80 Tablet
Swelling of ankles or feet
Increased heartbeat
Dizziness
Difficulty in breathing
Heartburn
Acid or sour stomach
Back pain
Stomach pain
Anxiety
Constipation or diarrhea
Sweating
Changes in vision
Difficulty or painful urination

Uses of Tazloc Trio 80 Tablet

What is it prescribed for?
Essential hypertension
This medicine is used in the treatment of high blood pressure which may be caused by genetic or environmental factors.

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to hydrochlorothiazide, other sulfonamides, amlodipine, other calcium-channel blockers, telmisartan, other angiotensin receptor blockers, or any other inactive ingredients present in the formulation.
Aliskiren
Coadministration of aliskiren and this combination medicine is not recommended due to the increased risk of serious adverse effects. This risk is especially higher in the elderly population and in patients with diabetes and kidney diseases.
Anuria
This medicine is not recommended for use in patients with anuria (a condition where the kidney is unable to produce urine) due to the increased risk of worsening of the patient’s condition.
Severe liver impairment
This medicine is not recommended for use in patients with severe liver impairment and in patients with cholestasis or biliary obstructive disorders due to the increased risk of worsening of the patient’s condition.
Severe kidney impairment
This medicine is not recommended for use in patients with severe kidney impairment (CrCl < 30 ml/min) due to the increased risk of serious adverse effects.

Warnings

Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings
Use in children
This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.
Coronary artery diseases
This medicine should be used with extreme caution in patients suffering from coronary artery diseases since it may worsen the patient’s condition. Close monitoring of heart function and vital signs is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Low blood pressure
Use of this medicine may increase the risk of low blood pressure levels (hypotension), especially in patients with volume depletion. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Liver impairment
This medicine should be used with caution in patients with liver impairment. Close monitoring of liver function is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Kidney diseases
This medicine may cause Azotemia in patients with a known history of severe kidney diseases. Close monitoring of kidney function is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Volume and electrolyte depletion
This medicine may alter the blood volume and electrolyte levels in some patients. This may cause dizziness, dry mouth, and acid-base imbalance. This risk is especially higher in patients suffering from kidney and liver diseases. Close monitoring of blood pressure and electrolyte levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Hyperkalemia
This medicine may increase potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (potassium-sparing diuretics and potassium supplements) during treatment with this medicine.
Driving and operating machines
This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Dosage

Missed Dose
The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine
Dexamethasone
Aliskiren
Captopril
Insulin
Antidepressants
Nonsteroidal anti-inflammatory medicines
Carbamazepine
Rifampicin
Disease interactions
Coronary Artery Disease
This medicine should be used with extreme caution in patients with coronary artery diseases due to the increased risk of worsening of the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Cardiogenic shock
This medicine is not recommended for use in patients suffering from a cardiogenic shock since it may worsen the patient’s condition.
Hyperuricemia
This medicine should be used with caution in patients with hyperuricemia since this medicine decreases the uric acid excretion and this may worsen the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Congestive heart failure
This medicine should be used with caution in patients with congestive heart failure due to the increased risk of worsening of the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Diabetes
This medicine should be used with caution in patients with diabetes mellitus due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels is advised for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
It is recommended to avoid a high potassium diet during treatment with this medicine due to the increased risk of serious adverse effects. Your doctor/dietitian will suggest an appropriate diet for you to avoid high intake of potassium.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take this medicine exactly as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.