About Pipzo 1.125gm Injection 1’s
Pipzo 1.125gm Injection 1’s belongs to the ‘Antibiotics’ class of drugs, primarily used to treat bacterial infections. It is used to treat various hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections (like diabetic foot infections) and uterine infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly.
Pipzo 1.125gm Injection 1’s contains two medicines, namely: Piperacillin (Penicillin antibiotic) and Tazobactam (beta-lactamase inhibitor). Piperacillin belongs to the class of ‘Penicillin antibiotics.’ It has bactericidal (ability to kill bacteria) activity against gram-positive and gram-negative aerobic (requires oxygen to survive) and anaerobic (survives with little or no oxygen) bacteria. Piperacillin acts by binding to the penicillin-binding proteins (PBPs) inside the bacterial cell wall and inhibits its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor. Beta-lactamases are the enzymes produced by bacteria to gain multi-resistance to β-lactam antibiotics, such as penicillins and cephalosporins. Tazobactam prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. In Pipzo 1.125gm Injection 1’s, Tazobactam works by preventing bacteria from destroying Piperacillin.
Pipzo 1.125 gm Injection 1’s is available in the form of intravenous injection. Like all medicines, Pipzo 1.125 gm Injection 1’s also causes side effects, although not everybody gets them. Common side effects of Pipzo 1.125gm Injection 1’s include nausea, constipation, diarrhoea, headache, and trouble sleeping. If any of these effects persist or worsen, seek medical advice promptly.
Brief your medical history to the doctor if you have any allergic reactions to antibiotics. Please inform your doctor if you have any liver, kidney diseases, bleeding disorders, and fits. Do not use Pipzo 1.125 gm Injection 1’s while having vaccinations with live bacterial vaccines (typhoid vaccine) since Pipzo 1.125gm Injection 1’s may affect vaccines’ activity. Pipzo 1.125 gm Injection 1’s should be used during pregnancy only if the doctor advised you. It is also excreted into breast milk in small amounts. Hence, it is recommended to consult your doctor if you are pregnant or breastfeeding before taking Pipzo 1.125gm Injection 1’s.
Uses of Pipzo 1.125gm Injection 1’s
Bacterial infections, hospital-acquired and ventilator-associated pneumonia, urinary tract infections, intra-abdominal infections, skin and soft tissue infections, and uterine infections.
Medicinal Benefits
Pipzo 1.125 gm Injection 1’s contains two medicines, namely: Piperacillin and Tazobactam. Piperacillin is a Penicillin antibiotic. It acts by binding to the penicillin-binding proteins (PBPs) inside the bacterial cell wall and inhibits its cell wall synthesis. Tazobactam is a beta-lactamase inhibitor that prevents the breakdown of other antibiotics by beta-lactamase enzyme producing organisms. In Pipzo 1.125gm Injection 1’s, Tazobactam works by preventing bacteria from destroying Piperacillin. Thus, Pipzo 1.125gm Injection 1’s helps treat various bacterial infections of the stomach, lungs, skin and uterus.
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Directions for Use
Storage
Side Effects of Pipzo 1.125gm Injection 1’s
- Nausea
- Constipation
- Diarrhoea
- Headache
- Trouble sleeping
In-Depth Precautions and Warning
Drug Warnings
If you have a history of any cystic fibrosis (damaged lungs and digestive system), kidney disease, fits, colitis (inflammation of the colon), bleeding disorders, heart or liver diseases, please inform your doctor before starting Pipzo 1.125gm Injection 1’s. Please tell your doctor if you are undergoing dialysis treatment since Penicillin antibiotics like Piperacillin are removed by haemodialysis. Your doctor may schedule the dosage after dialysis. Clostridium difficile associated diarrhoea (CDAD) is reported during usage of antibiotics like Pipzo 1.125gm Injection 1’s. Therefore, please undergo an examination to rule out the chances of CDAD if you experience diarrhoea following Pipzo 1.125gm Injection 1’s therapy.
Let your doctor know if you are undergoing any vaccinations with live bacterial vaccines (like typhoid vaccine) since Pipzo 1.125gm Injection 1’s may affect vaccines’ activity. Pipzo 1.125 gm Injection 1’s should be used with caution during pregnancy since it crosses the placenta in humans. Pipzo 1.125 gm Injection 1’s is also excreted into breast milk. Please seek medical advice if you are pregnant or breastfeeding before taking Pipzo 1.125 gm Injection 1’s. Patients aged above 65 years are not at an increased risk of having side effects. However, the dosage should be adjusted if the patient has a history of renal impairment. Sometimes, antibiotic medications can cause antibiotic resistance. In such cases, your doctor may prescribe other antibiotics, you are not resistant.
Drug Interactions
Drug-Drug Interaction: Pipzo 1.125gm Injection 1’s may interact with anticoagulants (heparin), anti-cancer drugs (methotrexate), antibiotics (tobramycin, vancomycin), gout medicines (probenecid), and anaesthetic drugs (vecuronium).
Drug-Food Interaction: Avoid alcohol consumption while taking Pipzo 1.125gm Injection 1’s to prevent unpleasant side-effects, such as nausea and vomiting.
Drug-Disease Interaction: Before taking Pipzo 1.125gm Injection 1’s, let your doctor know if you have cystic fibrosis, kidney disease, fits, colitis, bleeding disorders, heart or liver diseases, and are undergoing dialysis treatment.
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