INTRODUCTION
ENDACE 40MG contain megestrol which belongs to a group of medicine called progestogens and is related to the naturally occurring hormone called progesterone. It is used to treat certain types of cancer known as hormone-dependent cancer. Cancer is a disease in which abnormal cell divide uncontrollably and destroy body tissue. Hormone-dependent cancer is a type of cancer that is dependent on a hormone for growth and/or survival.
Hormones are substances produced naturally in the body and they act as chemical messengers and help control the activity of cells and organs. Hormone therapies interfere with the way hormones are made or formed in the body. Many types of cancer depend on hormones to grow. ENDACE 40MG may stop the cancer growing by changing this hormone balance in the body and slows down the growth of cancer. It can also act directly on cancer cell so that they cannot grow.
The most common side effects are increase in appetite, weight gain, hot flushes, high blood pressure, constipation, increased blood sugar levels. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.
USES OF ENDACE 40MG
- Treat certain types of cancer known as hormone-dependent
HOW ENDACE 40MG WORKS
ENDACE 40MG may stop the cancer growing by changing the hormone balance in the body and slows down the growth of cancer. It can also act directly on cancer cell so that they cannot grow.
DIRECTIONS FOR USE
Always take ENDACE 40MG exactly as your doctor has told you. It must be taken with or without food and try to take at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.
Dosage
SIDE EFFECTS OF ENDACE 40MG
SERIOUS
- Blood clot (signs include sudden loss of co-ordination, sudden slurred speech, pains in your arms, groin or leg (especially in calf of leg), sudden shortness of breath, weakness, numbness or pain in arm or leg, severe or sudden headache, fainting)
COMMON
- Changes in appetite or weight
- Water retention (swelling of ankles and feet)
- Nausea, vomiting
- Changes in vaginal bleeding (breakthrough bleeding, spotting)
- Shortness of breath
- Hot flushes
- Changes in mood
- Raised blood pressure
- Raised blood sugar
- Reddening of the face and neck
- Increased facial and body hair
- Urticaria (hives or nettle rash)
- Loss of scalp hair
- Pain or numbness in fingers
HOW TO MANAGE SIDE EFFECTS
Nausea and vomiting:
Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
WARNING & PRECAUTIONS
PREGNANCY
ENDACE 40MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
ENDACE 40MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
ENDACE 40MG do not usually affect your ability to drive.
ALCOHOL
Consumption of alcohol is not recommended during treatment with ENDACE 40MG.
KIDNEY
ENDACE 40MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
LIVER
ENDACE 40MG should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.
ALLERGY
Do not take ENDACE 40MG if you are allergic (hypersensitive) to megestrol or any other ingredients in this medicine.
OTHERS
Tell your doctor if you have or had a condition such as,
- A medical history of blood clot (thrombophlebitis)
- Blood sugar is higher than normal
INTERACTIONS
Tell your doctor about all the medicines you use, including prescription and non-prescription medicines and herbal supplements.
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