Description
Biobin 1000 mg injection is an anti-cancer medicine that contains cytarabine. It is used in the treatment of various types of blood and bone marrow cancers such as acute non-lymphocytic leukaemia (a type of cancer with excess immature white blood cells) and acute lymphocytic leukaemia (a type of cancer that affects white blood cells). It should only be used under medical supervision.
Biobin 1000 mg injection shows some side effects like hair loss, skin and mouth ulcers, rash, anaemia, sepsis (blood poisoning), low white blood cell count, nausea, vomiting, abdominal pain, pneumonia, infections, fever, anal ulcers, abnormal liver function and stomatitis (Inflammation of the mouth). Biobin 1000 mg injection does not cause drowsiness but it still may cause side effects that affect your ability to drive. Inform your doctor immediately if you feel sudden chills, notice unusual bruising or bleeding and black and tarry stools.
Biobin 1000 mg injection is not recommended for use in elderly patients. Inform your doctor if you have liver or kidney diseases before receiving this medicine. Close monitoring of liver function and the blood cell count is necessary while receiving this medication as it is known to affect the liver and bone marrow. Biobin 1000 mg injection is not recommended for use in pregnancy and breastfeeding.
Side effects
Major & minor side effects for Biobin 1000 mg injection
Nausea
Vomiting
Diarrhoea
Rash
Fever
Elevated Liver Enzymes
Bleeding
Headache
Chest pain
Joint pain
Anal ulcers
Skin ulcers
Hair loss
Anemia
Uses of Biobin 1000 mg injection
What is it prescribed for?
Acute Lymphocytic Leukemia
Biobin 1000 mg injection is used for the treatment of acute lymphocytic leukaemia (a type of cancer of the blood and the bone marrow) that affects white blood cells in adults and children.
Acute Non Lymphocytic Leukemia
Biobin 1000 mg injection is used for the treatment of Acute non-lymphocytic leukaemia which is a cancer of the blood and the bone marrow with myeloblasts (immature white blood cells) in adults.
When not to use?
Allergy
Avoid receiving Biobin 1000 mg injection if you have a known allergy to cytarabine, or any other inactive ingredients present in this formulation. Inform your doctor, if you notice any symptoms of serious allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness or breathing difficulty, etc.
Warnings
Warnings for special population
Pregnancy
Biobin 1000 mg injection is not recommended for use in pregnancy, because it may harm your foetus.
Breast-feeding
Biobin 1000 mg injection is not recommended for use in breastfeeding women because it may cause undesirable effects in infants.
General warnings
Use in Elderly
Biobin 1000 mg injection is not recommended to use in elderly patients as they can not tolerate drug toxicity.
Liver Disease
Biobin 1000 mg injection should be used with caution if you have liver diseases due to the increased risk of adverse effects. Your doctor may monitor your liver function regularly while receiving this medicine. Your doctor may adjust the dose if required based on your clinical conditions.
Driving or Operating machinery
Biobin 1000 mg injection may cause dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any dizziness during treatment with this medicine.
Bone marrow suppression
Biobin 1000 mg injection should be used with caution since it may increase the risk of myelosuppression (decreased bone marrow function). Regular monitoring of blood cell count is necessary while receiving this medicine. Your doctor may adjust the dose if required based on your clinical conditions.
Dosage
Missed Dose
Since Biobin 1000 mg injection is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of missing a dose is very low.
Overdose
Since Biobin 1000 mg injection is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
Interactions
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Thalidomide
Adalimumab
Digoxin
Methotrexate
Cyclophosphamide
Naltrexone
Vinblastine
Disease interactions
Infections
Biobin 1000 mg injection should be used with extreme caution if you have a history of recurrent infections due to the increased risk of myelosuppression (a condition in which bone marrow activity is decreased). Initiation of therapy with this medicine in patients with active infections is not recommended. Your doctor may monitor your condition while on treatment with this medicine if you have active infections.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
General Instructions
Biobin 1000 mg injection is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor after receiving this injection.
Inform the doctor if you have a known allergy to Biobin 1000 mg injection. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Use reliable contraception methods to prevent pregnancy if you are using Biobin 1000 mg injection.
Consult your doctor if you notice any fever, sore throat, rash or severe diarrhoea which may be signals of infection caused by using this medicine.
