Description
Zix MR 4 Tablet is a combination of Aceclofenac and Thiocolchicoside. It is a painkiller medicine that provides relief from the pain associated with muscle spasms such as low back pain, neck pain, sprains/strains, etc. It works by relaxing your muscles and preventing muscle contraction. It also prevents the release of a chemical substance that causes pain and swelling in your body.
Zix MR 4 Tablet can cause side effects such as nausea, vomiting, heartburn, stomach pain, diarrhoea, and sleepiness. These effects are mild and subside by themselves. Contact your doctor if they last for a long time or if they become severe.
Zix MR 4 Tablet can be taken with food to avoid stomach irritation. Your doctor will determine the dose and duration of treatment depending on the severity of your health condition. For the ease of remembering and better results, take it at around the same time every day. Avoid taking it for a longer duration than prescribed by your doctor as it may lead to undesired effects.
Zix MR 4 Tablet is not recommended for use if you are allergic to it. Inform your doctor if you have liver, kidney, or heart problems, or a history of stomach ulcers before starting treatment with this medicine. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding before taking this medicine.
Substitutes
List of substitutes for Zix MR 4 Tablet
AFENAC TH TABLET
Strides Shasun Ltd.
Aldigesic TH Tablet
Alkem Laboratories Ltd.
Movace MR Tablet
Alkem Laboratories Ltd.
Nise AT 4 Tablet
Dr. Reddys Laboratories Ltd.
Willgo TH 4 Tablet
Panacea Biotec Ltd.
Side effects
Major & minor side effects for Zix MR 4 Tablet
Dizziness
Nausea
Diarrhoea
Increased liver enzyme levels in the blood
Mouth ulcers
Rash or Itching
Drowsiness
Dry mouth
Stomach pain
Uses of Zix MR 4 Tablet
What is it prescribed for?
Acute inflammation associated with muscle spasm
Zix MR 4 Tablet is used to treat the pain and swelling associated with muscle spasms (a condition that causes involuntary contraction of muscles). It is used in conditions such as muscle pain, low back pain, neck pain, sprain/strains, etc. It is also used to relieve pain due to bone and joint conditions like ankylosing spondylitis (pain and stiffness of bones of the spine), osteoarthritis (tender and painful joints due to wear down of protective cartilage between the ends of the bones), rheumatoid arthritis (swelling and pain in the small joints of your body), etc.
When not to use?
Allergy
Avoid taking Zix MR 4 Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Gastrointestinal bleeding
Peptic ulcers are sores on the lining of your stomach and intestine. It may further lead to bleeding in the stomach and intestine. The symptoms are blood in stools/vomit, black coloured stool, and cramps in the stomach. Zix MR 4 Tablet is not recommended for use if you have active or a history of peptic ulcers and bleeding as it may worsen your condition.
Severe Liver/Kidney Impairment
Zix MR 4 Tablet is not recommended for use if you have severe liver and/or kidney problems. This medicine may further damage your liver and/or kidneys and worsen your condition.
Asthma
Asthma is a condition in which your airways narrow and cause breathing difficulty. Zix MR 4 Tablet is not recommended for use if you have a history of asthma after taking NSAIDs (non-steroidal anti-inflammatory medicines like Paracetamol, Ibuprofen, Aspirin, Aceclofenac, etc.).
Related Product
Zix P Tablet
Zix S Tablet
Zix-MR 8mg Tablet
Zix-MR Tablet
Zixflam Tablet
Zix-PG 200/75 Tablet
Warnings
Warnings for special population
Pregnancy
Zix MR 4 Tablet is not recommended for use during pregnancy as it may harm your foetus.
Breast-feeding
Zix MR 4 Tablet is not recommended for use while breastfeeding as it may pass into breastmilk. Hence, consult your doctor if you are breastfeeding before taking this medicine.
General warnings
Other medicines
Zix MR 4 Tablet may interact with other medicines and cause undesired side effects. Hence, inform your doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.
Driving and operating machines
Zix MR 4 Tablet may cause dizziness and sleepiness. Avoid driving or operating machines if you experience such symptoms after taking the medicine.
Use in children
Zix MR 4 Tablet is not recommended for use in children below 18 years of age due to a lack of safety and efficacy data.
Impairment of fertility in men
Zix MR 4 Tablet may cause damage to sperm cells and lead to fertility problems in men. Therefore, discuss all the risks and benefits with your doctor before taking this medicine.
Women of childbearing potential
Women of childbearing potential should use effective contraceptive measures to avoid pregnancy during treatment with Zix MR 4 Tablet. A pregnancy test should be done to rule out pregnancy before beginning the treatment. If pregnancy is suspected during treatment, consult your doctor for further guidance.
Dosage
Missed Dose
Try not to skip a dose of Zix MR 4 Tablet. Take the missed dose as soon as you remember. If it is time for your next dose, skip the missed one. Do not double the dose to compensate for a missed one.
Overdose
Never take more than the prescribed dose. Contact your doctor in case of an overdose with Zix MR 4 Tablet for further guidance.
Interactions
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during treatment with Zix MR 4 Tablet as it may increase the risk of side effects such as stomach and intestinal bleeding, and excessive drowsiness.
Interaction with Medicine
Lithium
Digoxin
Corticosteroids
Antihypertensives
Warfarin
Disease interactions
Kidney Disease
Use Zix MR 4 Tablet with caution if you have kidney problems. Prolonged use of high doses of this medicine may further damage your kidneys. Hence, your doctor may suggest tests to closely monitor your kidney function while taking this medicine.
Liver Disease
Use Zix MR 4 Tablet with caution if you have pre-existing liver problems due to the increased risk of side effects. It may also cause further liver damage. Your doctor may suggest tests to closely monitor your liver function while taking this medicine.
Heart Disease
Avoid long-term use of a high dose of Zix MR 4 Tablet if you have pre-existing heart conditions like heart failure (a condition in which your heart is unable to pump a sufficient amount of blood), ischaemic heart diseases (heart problems due to narrowing of the blood vessels that supply oxygen to the heart), etc. This medicine may cause fluid retention (abnormal build-up of fluid in the body tissues) and also increase the risk of a heart attack. Consult your doctor before taking this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
General Instructions
Take Zix MR 4 Tablet with or after food to avoid stomach irritation. Do not break, chew or crush the tablet.
Avoid taking more or less than the prescribed dose. Take this medicine for the recommended duration. Avoid the discontinuation of this medicine without consulting your doctor as your symptoms may come back.
Avoid consuming alcohol while taking Zix MR 4 Tablet as it may increase your risk of stomach bleeding.
Avoid driving or operating machines if you experience any symptoms that may affect your mental alertness after taking Zix MR 4 Tablet.
