INTRODUCTION
ZILARBI contain Azilsartan medoxomil which belongs to a group of medicine called angiotensin II receptor antagonists (AIIRAs). Angiotensin II is a substance occur naturally in body which tightens the blood vessels, thereby increasing your blood pressure. This medicine blocks this effect so that the blood vessels relax which helps lower your blood pressure.
It is used for treating high blood pressure (essential hypertension) in adult patients (over18 years of age). High blood pressure is a condition in which the force of the blood against the artery walls is high. The common side effects are dizziness, diarrhoea, increased blood creatine phosphokinase. It is not recommended for use in children and adolescents under 18 years. Before taking this medicine tell your doctor if you have ever had kidney, heart or liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.
USES OF ZILARBI
- Treat high blood pressure
HOW ZILARBI WORKS
ZILARBI works by relaxing the blood vessel by blocking the action of a chemical that usually makes blood vessels tighter. This lowers the blood pressure and allows the blood to flow more smoothly to different organs and the heart to pump more efficiently.
DIRECTIONS FOR USE
Always take ZILARBI exactly as your doctor has told you. This medicine must be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.
SIDE EFFECTS OF ZILARBI
SERIOUS
- Allergic reactions such as difficulties in breathing, or swallowing, or swelling of the face, lips, tongue, throat (angioedema), itching of the skin with raised lumps
COMMON
- Dizziness
- Diarrhoea
- Increased blood creatine phosphokinase (an indicator of muscle damage)
RARE
- Changes in blood test results including decreased levels of a protein in the red blood cells (haemoglobin)
HOW TO MANAGE SIDE EFFECTS
Dizziness:
Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
Diarrhoea:
Drink lot of fluid such as water or squash, to avoid dehydration. Do not take any other medicines without talk to a doctor.
WARNING & PRECAUTIONS
PREGNANCY
ZILARBI is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
ZILARBI is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate any machine while taking this medicine, since it may cause tiredness or dizziness.
ALCOHOL
Consumption of alcohol is not recommended during treatment with ZILARBI.
KIDNEY
ZILARBI is not recommended in patients with active kidney diseases. Before taking, discuss the risks and benefits with your doctor.
LIVER
ZILARBI should be used with caution in patients suffering from liver function impairment or active liver diseases. Consult your doctor for advice.
ALLERGY
Do not take ZILARBI if you are allergic (hypersensitive) to azilsartan medoxomil or any other ingredients in this medicine.
HEART DISEASE
ZILARBI should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.
OTHERS
Tell your doctor if you have or had condition such as,
- Diabetes
- Ever had a stroke
- Low blood pressure or feel dizzy or lightheaded
- Recent severe vomiting, or have diarrhoea
- Raised levels of potassium in your blood (as shown in blood tests)
- A disease of the adrenal gland called primary hyperaldosteronism
INTERACTIONS
Talk to your doctor if you are taking,
- Lithium (used to treat mental health problems)
- Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, diclofenac, or celecoxib (used to treat pain and inflammation)
- Acetylsalicyclic acid (used to treat pain and inflammation)
- Potassium supplements, potassium-sparing medicines or salt substitutes containing potassium (used for increasing the amount of potassium in your blood)
- Heparin (used for thin blood)
- Diuretics
- Aliskiren or other medicine to lower your blood pressure (angiotensin converting enzyme inhibitor or angiotensin II receptor blocker such as enalapril, lisinopril, ramipril or valsartan, telmisartan, irbesartan
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