TRETIVA 40MG
Tretiva 40mg Capsule is a medicine that contains isotretinoin. It is a naturally occurring derivative of vitamin A. This medicine is used for the treatment of a severe form of acne called nodular acne characterized by large, inflamed, painful acne lesions deep under the skin. It acts on skin glands to reduce the production of a substance called sebum that can cause acne or pimples. It also has an anti-inflammatory action which decreases the redness and swelling associated with acne.
Tretiva 40 MG Capsule has some common side effects like cracked lips, dry eye, dry nose, dry skin and dry mouth. Consult your doctor if any of these side effects persist or bother you. Do not take this medicine if you are allergic to it.
Tretiva 40 MG Capsule should be taken with food. Take this as prescribed by your doctor. Complete the whole treatment, even if you feel better after taking a few doses. Use skin protective methods like wearing sunscreen and having a balanced diet along with Tretiva 40 MG Capsule for the treatment of acne.
Tretiva 40 MG Capsule is not recommended to be used in pregnancy and breastfeeding. Inform your doctor if you have liver problems before taking this medicine. It is not recommended for use in children under 12 years of age.
Tretiva 40 MG Capsule may cause skin sensitivity to sunlight so it is advised that you avoid going out in harsh sunlight or take precautions like sunscreen. You should avoid alcohol consumption while taking this medicine as it may cause severe side effects. Inform your doctor immediately if you experience and serious side effects like changes in mood or depression, dizziness, ringing in ears, headache, problems with vision, pain behind the eyes, increased thirst and urination while using this medicine.
Substitutes
List of substitutes for Tretiva 40 MG Capsule
Sotret 40 MG Capsule
Ranbaxy Laboratories Ltd.
Side effects
Major & minor side effects for Tretiva 40 MG Capsule
Changes in skin color
Bleeding from nose
Scaling, burning, redness, and swelling of skin
Burning, dry and itchy eyes
Itchy and dry skin
Bleeding or swollen gums
Changes in the nail color
Hair loss
Sweating
Ringing or buzzing in the ears
Yellow colored eyes or skin
Uses of Tretiva 40 MG Capsule
What is it prescribed for?
Nodular acne
Nodular acne is large, painful nodes formed deep under the skin, resulting in a red or skin-coloured bump. These bumps are firm, sensitive, and painful. It is caused by bacteria on the skin and can turn into an infection that can go deep beneath your skin, causing the affected pores to become red and swollen. Tretiva 40 MG Capsule is used for the treatment of nodular acne when other medicines are ineffective in treating this condition.
Related Products
Tretiva 5 mg Capsule
Tretiva 10 mg Capsule
Tretiva 20 mg Capsule
Tretiva 25 mg Capsule
Tretiva 30 mg Capsule
Tretiva 40 mg Capsule
When not to use?
Allergy
Avoid using Tretiva 40 MG Capsule if you are allergic to isotretinoin or any other component present in this medicine. Seek medical help immediately if you notice any symptoms such as skin rashes, itching/swelling, dizziness, breathing difficulty, etc.
Hypervitaminosis A
Hypervitaminosis A is a condition that occurs when you have too much vitamin A in your body. Symptoms of hypervitaminosis A include vision problems, changes in the skin, and bone pain. In such cases Tretiva 40 MG Capsule is not recommended for use as it is also a derivative of vitamin A and it may worsen your condition.
Severe liver disease
Tretiva 40 MG Capsule is not recommended for use if you have severe liver conditions as it may worsen your condition.
Warnings
Warnings for special population
Pregnancy
Tretiva 40 MG Capsule is not recommended to be used in pregnancy as it can cause birth defects in your unborn child. Even a single dose of Tretiva 40 MG Capsule can result in birth defects. Consult your doctor to know the risks and benefits of this medicine.
Breast-feeding
Tretiva 40 MG Capsule is not recommended to be used in breastfeeding as it may pass into breast milk. This can potentially harm your child. Consult your doctor to know the risks and benefits of this medicine.
General warnings
Exposure to sun
The use of Tretiva 40 MG Capsule may cause severe side effects on sun exposure. You are advised to stay away from sunlight until finishing the course of the treatment. Take appropriate precautionary measures like covering your skin, use high SPF sunscreen etc., before stepping out during treatment with this medicine.
Contraception
Tretiva 40 MG Capsule can cause oral/hormonal contraceptive medicine failure, so the use of multiple contraceptive methods is advised. Appropriate means of birth control should be adopted while using Tretiva 40 MG Capsule to avoid pregnancy.
Donation of blood
It is advised to refrain from donating blood for 1 month after stopping the use of Tretiva 40 MG Capsule because of the potential risk to an unborn baby of a pregnant transfusion recipient.
Diabetes
Tretiva 40 MG Capsule may alter blood glucose levels and hence should be used with extreme caution in people with diabetes mellitus. Close monitoring of the blood glucose levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Hearing loss
The use of Tretiva 40 MG Capsule has been associated with hearing loss which may persist even after the use is discontinued. You should immediately contact your doctor if you face any hearing issues.
Disturbance in vision
The use of Tretiva 40 MG Capsule may cause dry eyes, decreased night vision and loss of transparency of cornea that could persist even after stopping the treatment. Contact your doctor immediately if you experience any issues with your vision.
Hyperlipidaemia
Tretiva 40 MG Capsule has been associated with an increased level of lipids and triglycerides in the body and hence should be used with caution if you have hyperlipidaemia and other associated disorders. Your doctor may adjust the dose of this medicine if required based on your condition.
Driving or operating machinery
Tretiva 40 MG Capsule may rarely cause dizziness, drowsiness, visual disturbances, etc. in some people. It is advised that you do not perform any activities that require high mental alertness like driving vehicles or operating machines if you experience any of these symptoms after taking this medicine.
Depression
Tretiva 40 MG Capsule has been known to cause varying levels of depression. Report any current/past incidences of depression, agitation, anxiety, or other psychotic disorders to your doctor while on treatment with this medicine.
Dosage
Missed Dose
Do not skip a dose of Tretiva 40 MG Capsule. If you forget to take a dose of this medicine, take it as soon as you remember. If it is time for your next dose, skip the missed one. Do not double the dose to compensate for the missed one.
Overdose
If you have taken more than the prescribed dose of Tretiva 40 MG Capsule you may experience symptoms like vomiting, flushing, severely chapped lips, stomach pain, headache and dizziness. Consult with your doctor immediately in case of an overdose.
Interactions
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Avoid consumption of alcohol while taking Tretiva 40 MG Capsule as it may cause unpleasant side effects such as rapid heartbeat, warmth or redness under your skin, tingly feeling, nausea, and vomiting.
Interaction with Medicine
Methoxsalen
Natural Micronised Progesterone
Doxycycline
Tetracycline
Daclizumab
Disease interactions
Intracranial hypertension
Tretiva 40 MG Capsule is not recommended as it is associated with cases of pseudotumor cerebri (when the pressure inside the skull increases). Early signs and symptoms include papilledema, headache, nausea and vomiting, and visual disturbances.
Psychiatric disorders
Tretiva 40 MG Capsule has been associated with causing depression, psychosis and an increase in suicidal behaviour. It should be administered cautiously and with supervision, if you have any preexisting psychiatric conditions or depression. Your doctor may adjust the dose of this medicine or suggest alternatives if required based on your condition.
Osteoporosis
Tretiva 40 MG Capsule may cause a reduction in bone density and hence should be used with caution if you have osteoporosis or other disorders affecting bone density. Your doctor may adjust the dose of this medicine or suggest alternatives if required based on your condition.
Liver disease
Tretiva 40 MG Capsule should be used with extreme caution if you have liver problems as it is associated with elevations in liver enzymes and hepatitis. Your doctor may suggest tests to monitor your liver functioning and may adjust the dose of this medicine if required based on your condition.
Pancreatitis
Tretiva 40 MG Capsule should be used with caution if you have a pancreatic disorder as it may worsen your condition. Your doctor may suggest tests to monitor your pancreatic condition and may adjust the dose of this medicine if required based on your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
General Instructions
Take Tretiva 40 MG Capsule as instructed by your doctor. Follow all the directions mentioned on the label. Do not take more or fewer doses than prescribed.
This medicine should be taken with food. The symptoms might get worse in the initial phase of treatment.
It is advisable to avoid sunlight during the course of treatment. Take plenty of water and have a clean nutritious diet.
Keep away from the reach of children and pets. Ensure that unused medicine is disposed of properly.
