INTRODUCTION
RANX 1GM contains ranolazine which belongs to a class of medications called anti-anginal used to treat repeated angina (chronic angina). It may be used with other medicines which are used for heart problems and blood pressure control. Ranolazine decreases the inflow of sodium by the slow sodium current during ischemia and thereby lessens the intracellular sodium and calcium load. It is not known if this medicine is safe and effective in children.
This medicine is used in combination with other medicines to treat angina pectoris characterized by chest pain or discomfort between your neck and upper abdomen due to exercise or too much activity. You must talk to your doctor if you do not feel better or worse.
Always take RANX 1GM exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water. While being treated with this medicine, you should not drink grapefruit juice. Tell your doctor if you are using or recently used or might use any other medicines. Do not drive or operate any machinery while taking this medicine, it may make you feel dizziness, blurred vision. The most common side effects include dizziness, headache, nausea or vomiting, constipation and feeling weak.
USES OF RANX 1GM
- Treat repeated angina (chronic angina)
- Used in combination with other medicines to treat heart problems and high blood pressure
HOW RANX 1GM WORKS
This medicine acts by decreasing the inflow of sodium by the slow sodium current during ischemia and thereby lessens the intracellular sodium and calcium load. Reduction in Ca2+ overload in the myocardium during ischaemia decreases contractility and has a cardioprotective effect.
DIRECTIONS FOR USE
Always take RANX 1GM exactly as prescribed by your doctor. Swallow the medicine whole with plenty of water. Do not crush or chew the medicine.
SIDE EFFECTS OF RANX 1GM
SERIOUS
- Feel faint, lightheaded or feel your heart beat irregularly or fast
COMMON
- Dizziness, headache
- Nausea or vomiting
- Constipation
- Feeling weak
RARE
- A lack of ability to urinate
- Abnormal laboratory values for liver
- Acute kidney failure
- Change in sense of smell, numbness in mouth or lips
- Cold sweat, rash
- Coordination problems
- Decrease in blood pressure upon standing
- Decreased or loss of consciousness
- Disorientation
- Feeling of coldness in hands and legs
- Hives, allergic skin reaction
HOW TO MANAGE SIDE EFFECTS
Constipation:
Eat fiber rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.
Nausea and vomiting:
Keep try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Dosage
WARNING & PRECAUTIONS
PREGNANCY
RANX 1GM is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
RANX 1GM is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate any machinery while taking this medicine, it may make you feel dizziness, blurred vision.
ALCOHOL
Consumption of alcohol is not recommended during treatment with RANX 1GM.
KIDNEY
RANX 1GM should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
LIVER
RANX 1GM should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
ALLERGY
Do not take RANX 1GM if you are allergic (hypersensitive) to ranolazine or any other ingredients in this medicine.
HEART DISEASE
If you have any heart related problems, consult your doctor for advice before taking this medicine.
INTERACTIONS
Talk to your doctor if you are taking medicines to treat:
- Bacterial infections (clarithromycin, telithromycin)
- Fungal infections (itraconazole, ketoconazole, voriconazole)
- HIV infection
- Depression
- Heart rhythm disorders (e.g. quinidine, dofetilide, or sotalol)
- Epilepsy or any another neurologic disorder (e.g. phenytoin, carbamazepine or phenobarbital)
- Allergies (e.g. terfenadine, astemizole, mizolastine)
- High levels of cholesterol in the blood (e.g. simvastatin, lovastatin, atorvastatin)
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