Periset 8mg Tablet (Ondansetron)

Periset 8mg Tablet

Periset 8 MG Tablet is an antiemetic medicine used to treat and prevent nausea and vomiting caused by surgery, cancer medicines (chemotherapy) or radiation therapy. It works by blocking a natural substance called serotonin in the brain that causes nausea and vomiting. This medicine starts to work in 1 to 2 hours.

Common side effects of Periset 8 MG Tablet are constipation, headache and dizziness. Do not use this medicine if you are previously allergic to it. Inform your doctor if you have any disease conditions like liver disease, heart failure, slow heartbeats, electrolyte imbalance, stomach or intestine blockage disorders before using this medicine. Always make sure that Periset 8 MG Tablet is safe for you to use.

You may have to take this ondansetron tablet 30 minutes before the start of chemotherapy, 1-2 hours before the start of radiation therapy, or 1 hour before surgery. If you vomit this medicine within one hour of taking it, then you need to repeat the dose.

Substitutes

List of substitutes for Periset 8 MG Tablet
Emeset 8 MG Tablet
Cipla Ltd.
Emeset Od 8 MG Tablet
Cipla Ltd.
Setronem 8 MG Tablet
Strides Shasun Ltd.
Zofer 8 MG Tablet
Sun Pharma Laboratories Ltd.
Zondan 8 MG Tablet
Glaxosmithkline Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Periset 8 MG Tablet
Headache
Constipation
Excessive sweating
Chills
Anxiety
Dry mouth
Fast or slow or irregular heartbeat
Dizziness

Uses of Periset 8 MG Tablet

What is it prescribed for?
Radiation induced nausea and vomiting
Radiation-induced nausea and vomiting (RINV) is a common side effect in cancer patients undergoing radiotherapy. You may feel sick during, or for a short time after, radiotherapy treatment. Periset 8 MG Tablet is used to treat nausea and vomiting in patients treated with radiotherapy.
Chemotherapy induced nausea and vomiting
Chemotherapy-induced nausea and vomiting (CINV) is a common side-effect related to cancer treatment. This can be severe and distressing in patients with cancer receiving chemotherapy. Periset 8 MG Tablet is used to treat nausea and vomiting caused during chemotherapy treatment.
Post operative nausea and vomiting
Postoperative nausea and vomiting (PONV) describe nausea and vomiting that occurs immediately after the surgery which can also continue for a day or two. It can occur due to some medications like anaesthetics that are used during surgery. Periset 8 MG Tablet is used to treat nausea and vomiting in post-operative patients.

Dosage

Periset 8mg Tablet
Periset Injection
Periset Injection 10ml
Periset MD 4mg Tablet

When not to use?

Allergy
Avoid taking Periset 8 MG Tablet if you are previously allergic to it. Allergic reactions to this medicine are rare. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.
Apomorphine
Apomorphine is used to treat symptoms of Parkinson’s disease. The combined use of Periset 8 MG Tablet and apomorphine is not recommended due to the risk of lightheadedness, loss of consciousness, and low blood pressure.

Warnings

Warnings for special population
Pregnancy
Periset 8 MG Tablet is relatively safe to use in pregnant women. It is sometimes used to treat nausea and vomiting during the first trimester. But it is known to cause birth defects, particularly heart and kidney defects and therefore should only be used upon your doctor’s recommendation.
Breast-feeding
It is not known whether Periset 8 MG Tablet can be used in breastfeeding mothers or not. An alternate medication may be preferred, especially while nursing a newborn or preterm infant. However, your doctor may prescribe this medicine if the benefits outweigh the risks.
General warnings
Electrolyte imbalances
Low levels of potassium or magnesium in the blood should be corrected before starting treatment with Periset 8 MG Tablet.
Intestinal obstruction
Use Periset 8 MG Tablet cautiously in patients with intestinal obstruction diseases such as colon cancer, Crohn’s disease or diverticulitis because this medicine can delay the time for food to move through the entire intestine (bowel transit time).
Serotonin syndrome
Serotonin syndrome is a condition where your body produces too much of a chemical called serotonin. This occurs when you take medicines that cause high levels of serotonin in your body. This chemical helps your brain cells and nerve cells to communicate with each other. But too much serotonin causes extreme nerve cell activity and serious symptoms. Caution should be taken when Periset 8 MG Tablet is used along with other same class of medications like granisetron, dolasetron, etc., as it may increase the risk of serotonin syndrome.

Dosage

Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose with Periset 8 MG Tablet.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Amitriptyline
Phenytoin
Tramadol
Amiodarone
Apomorphine
Carbamazepine
Disease interactions
QT Prolongation
Periset 8 MG Tablet may cause a heart rhythm problem called prolonged QT intervals (an electrical heartbeat disturbance) in some patients who are taking heart medications. It may result in fast, rapid, and irregular heartbeats.
Liver Disease
The primary conversion of Periset 8 MG Tablet to its active form happens in the liver. Therefore patients with liver diseases need special consideration while taking Periset 8 MG Tablet.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Periset 8 MG Tablet as instructed by your doctor. Avoid eating heavy meals before taking ondansetron. Eat small snacks or light foods and also drink water to avoid dehydration while taking this medicine.
Ondansetron tab is available as strength of ondansetron 4 mg tablet, ondansetron 8 mg tablet and ondansetron 24 mg tablet.