About Grandem 1mg Injection
GRANDEM 1 MG INJECTION 1ML belongs to the class of ‘anti-emetic’ drugs, primarily used to treat nausea and vomiting caused by medical treatments, such as chemotherapy or radiation treatment for cancer, etc. Nausea is defined as stomach discomfort and the sensation of an urge to vomit. Vomiting is the forcible voluntary or involuntary emptying of contents of the stomach through the mouth.
GRANDEM 1 MG INJECTION 1ML contains an anti-emetic (eases vomiting symptoms) drug, ‘Granisetron’ that belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). It works by blocking the activity of serotonin (chemical messenger) in the brain that triggers nausea and vomiting during cancer treatment (chemotherapy or radiation therapy) or after surgery.
GRANDEM 1MG INJECTION 1ML is available in oral tablet, syrup and intravenous injection formulations. Your doctor will decide the dose and duration based on the severity of your medical condition. Common side effects of GRANDEM 1MG INJECTION 1ML include diarrhoea, constipation, stomach pain, weakness, headache, fever, dizziness, drowsiness, trouble sleeping and anxiety. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.
If you use other prescription or non-prescription medicines, inform your doctor before using GRANDEM 1MG INJECTION 1ML. Let your doctor know if you have any liver, kidney or heart diseases, stomach/intestinal problems, allergic reactions and low levels of potassium and magnesium in the blood before starting GRANDEM 1MG INJECTION 1ML. GRANDEM 1MG INJECTION 1ML may make you dizzy or drowsy, hence avoid driving if you are not mentally alert. Consult your doctor before taking GRANDEM 1 MG INJECTION 1ML if you are pregnant, planning for pregnancy or breastfeeding. Avoid consuming alcohol along with GRANDEM 1MG INJECTION 1ML as it could lead to increased drowsiness.
Uses of Grandem 1mg Injection
Nausea and vomiting.
Medicinal Benefits
GRANDEM 1MG INJECTION 1ML contains an anti-emetic drug, ‘Granisetron’ that treats nausea and vomiting caused due to cancer treatment (chemotherapy or radiation therapy) or after surgery, etc. Granisetron belongs to the class of 5-HT3 receptor antagonists (also called serotonin receptor antagonists or serotonin blockers). When the cells lining the gastrointestinal tract are damaged by chemotherapy or radiation therapy, they release a natural substance called serotonin (5HT3, 5-hydroxytryptamine). This serotonin binds to serotonin receptors on nerves that induces nausea and vomiting. GRANDEM 1MG INJECTION 1ML works by blocking the activity of serotonin in the brain and prevent post-operative nausea and vomiting.
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Directions for Use
Storage
Side Effects of Grandem 1mg Injection
- Diarrhoea
- Constipation
- Stomach pain
- Weakness
- Headache
- Fever
- Dizziness
- Drowsiness
- Trouble sleeping
- Anxiety
In-Depth Precautions and Warning
Drug Warnings
GRANDEM 1MG INJECTION 1ML may cause serotonin syndrome/toxicity when used with other drugs like ecstasy (MDMA) and antidepressants. Hence it is suggested to seek medical advice if you are using any prescription or non-prescription medicines. Inform your doctor if you have a history of stomach/intestinal problems like stomach ache, wind, feeling or being sick, difficulty passing stools, heart problems, electrolyte imbalance (potassium, sodium or calcium), heart problems and liver or kidney diseases before starting GRANDEM 1MG INJECTION 1ML. GRANDEM 1MG INJECTION 1ML may affect the heart rhythm (QT prolongation) and cause fast/irregular heartbeat, hence check with your doctor before starting GRANDEM 1MG INJECTION 1ML if you have any heart problems. Please consult your doctor if you are pregnant or breastfeeding if the doctor advised you GRANDEM 1MG INJECTION 1ML. GRANDEM 1MG INJECTION 1ML may make you feel dizzy, so drive only if you are alert. Avoid consuming alcohol along with GRANDEM 1MG INJECTION 1ML as it could lead to increased dizziness. GRANDEM 1MG INJECTION 1ML is not recommended in children below two years of age.
Drug Interactions
Drug-Drug Interaction: Grandem 1mg INJECTION 1ML may interact with antidepressants (lithium, fluoxetine, paroxetine, duloxetine, venlafaxine), street drugs (MDMA or 3,4-Methylenedioxymethamphetamine), heart-related drugs (amiodarone, dofetilide, procainamide, quinidine and sotalol), antipsychotic drugs (pimozide), HIV/AIDS drugs (ritonavir), antibiotics (erythromycin) and St. John’s wort, a plant-based medicine used for depression and mood disorders.
Drug-Food Interaction: Alcohol may increase dizziness when taken with GRANDEM 1MG INJECTION 1ML.
Drug-Disease Interaction: Before using GRANDEM 1MG INJECTION 1ML, let your doctor know if you have any stomach/intestinal problems like stomach ache, wind, feeling or being sick or difficulty passing stools, heart problems, electrolyte imbalance (potassium, sodium or calcium), heart problems and liver or kidney diseases.
