Oestrogel Gel 0.06% (Estradiol)

Description

Oestrogel 0.06% Gel contains female hormone estrogen (female sex hormone). It is used to relieve symptoms occurring after menopause (cessation of menses) such as vaginal dryness/burning/itching, hot flashes, etc.

Oestrogel 0.06% Gel shows side effects like stomach pain, headache, changes in weight, oedema (swelling) of legs, breast tenderness, mood alterations including anxiety and depressed mood.

Oestrogel 0.06% Gel is recommended to be taken at the same time every day. Your doctor will decide the dosage of this medicine based on the indication you are taking it for.

Oestrogel 0.06% Gel is not recommended for use if you have abnormal/unusual vaginal bleeding. Inform your doctor if you have any kidney problems, diabetes, or any other medical conditions. Do not take this medicine if you are pregnant or planning a pregnancy. Inform your doctor if you are breastfeeding to understand its benefits and the risk to your infant.

Substitutes

List of substitutes for Oestrogel 0.06% Gel
E 2 0.06% Gel
Sun Pharma Laboratories Ltd.
Side effects
Major & minor side effects for Oestrogel 0.06% Gel
Depression
Nervousness
Headache
Abdominal pain
Rash
Itching of skin
Increased sweating
Edema at the site of application

Uses of Oestrogel 0.06% Gel

What is it prescribed for?
Post menopausal symptoms
Post-menopausal symptoms are that you experience after menopause (end of menstrual cycles). These symptoms may include vaginal dryness/itching, hot flushes, irritability, and mood swings. Oestrogel 0.06% Gel works by balancing the level of hormones (chemical messengers) that cause these symptoms in your body.
Vaginal/vulvar atrophy
Vaginal/vulvar atrophy is thinning and shrinking of tissues in the urethra (the tube that drains urine from the bladder) and the vagina. It also leads to decreased lubrication due to a lack of hormone estrogen. Oestrogel 0.06% Gel is used to treat such conditions.

When not to use?

Allergy
Avoid taking Oestrogel 0.06% Gel if you are allergic to it. Allergic reactions are rare; however, contact your doctor immediately if you experience symptoms like rashes, itching/swelling (particularly of your face/tongue/throat), severe dizziness, and breathing difficulty, etc.
Undiagnosed vaginal bleeding
Oestrogel 0.06% Gel is not recommended for use if you have an abnormal vaginal bleeding episode that has not been diagnosed by your doctor. If you have any menstrual abnormalities, consult your doctor first before taking this medicine.
Heart and blood vessel disorder
Oestrogel 0.06% Gel is not recommended if you have an active or history of stroke (decreased blood flow to your brain) or heart attack. This medicine should also be avoided if you have blood clotting issues. Oestrogel 0.06% Gel can lead to an increase in clot formation if taken in higher doses and thus can worsen your condition.
Estrogen-dependent tumor
Oestrogel 0.06% Gel is not recommended if you have cancer that is sensitive to oestrogens, such as breast and cancer of the endometrium (womb lining), or if you are suspected of having it.
Liver disease
Liver tumours are types of cancer that form in the liver. Oestrogel 0.06% Gel is not recommended in liver tumours because long term use of this medicine may worsen your condition.
Porphyria
Porphyria is a disorder resulting from the accumulation of certain chemicals related to blood cell proteins. Oestrogel 0.06% Gel is not recommended in the presence of porphyria.

Warnings

Warnings for special population
Pregnancy
Oestrogel 0.06% Gel is for use in postmenopausal women (when you have not had your menses for over a year) only.
Breast-feeding
Oestrogel 0.06% Gel is for use in postmenopausal women (when you have not had your menses for over a year) only.
General warnings
Breast cancer
Oestrogel 0.06% Gel increases the risks of breast cancer, hence should be used at the lowest doses and the duration of treatment should be kept as low as possible.
Oedema
Oestrogel 0.06% Gel may cause fluid retention or other associated problems in women. Inform the doctor if you experience any symptoms like swelling of your eye, throat, tongue, arms, and feet.
Use in children
Oestrogel 0.06% Gel is not recommended for use in children and adolescents below 18 years of age as safety and efficacy is not known.

Dosage

Missed Dose
Apply the missed dose of Oestrogel 0.06% Gel as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.
Overdose
An overdose of this medicine is not likely to cause severe symptoms unless it is applied for a prolonged period of time in large volumes. However, ingestion of Oestrogel 0.06% Gel may cause harm and immediate medical intervention may be required.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Benzalkonium chloride
Phenobarbital
Disease interactions
Abnormal vaginal bleeding
Oestrogel 0.06% Gel should be avoided when there is abnormal vaginal bleeding. Your doctor may advise this medication once the bleeding stops.
Hypertension
Hypertension is a condition in which your blood pressure level is higher than normal. Use Oestrogel 0.06% Gel with caution if you have hypertension because it may increase the risk of heart attack and stroke (decreased blood flow to your brain).
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Apply a thin layer of Oestrogel 0.06% Gel as instructed by your doctor. Follow all the usage instructions mentioned on the label or the package insert.

Do not apply in larger or smaller quantities than recommended.

The applied gel should be allowed to dry and should not be washed within 1 hour of application.