About Neksium D 40 Capsule 10’s
Neksium D 40 Capsule 10’s belongs to a group of gastrointestinal agents to treat acidity, heartburn, gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, nausea, vomiting, dyspepsia (indigestion), epigastric pain, peptic ulcers, and eradication of helicobacter pylori infection. Neksium D 40 Capsule 10’s is a sustained release formulation that prolongs drug release for a longer duration of time.
Neksium D 40 Capsule 10’s is a combination of two drugs: Esomeprazole (proton pump inhibitor) and Domperidone (a dopamine antagonist). Esomeprazole works by blocking an enzyme called gastric proton pump, which is responsible for the production of acid Domperidone works by increasing the movements and contractions of stomach muscle. Together, Neksium D 40 Capsule 10’s helps in treating acidity-related problems.
Take Neksium D 40 Capsule 10’s 1hour before food. Swallow Neksium D 40 Capsule 10’s as a whole with a glass of water; do not chew or break the tablet. You are advised to take Neksium D 40 Capsule 10’s for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dry mouth, stomach pain, diarrhea, headache, and flatulence. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Inform your doctor before taking Neksium D 40 Capsule 10’s if you have severe kidney or liver disease; if you are due to have Chromogranin A blood test, have fungal infections, heart problems, or HIV infection. Talk to your doctor before taking Neksium D 40 Capsule 10’s if you have osteoporosis: Neksium D 40 Capsule 10’s may increase the risk of bone fractures on long-term treatment. Consult your doctor before taking Neksium D 40 Capsule 10’s if you are pregnant or breastfeeding. Neksium D 40 Capsule 10’s may cause dizziness, so drive only if you are alert. Neksium D 40 Capsule 10’s should not be given to children as safety has not been established. Avoid consuming alcohol and Neksium D 40 Capsule 10’s as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Uses of Neksium D 40 Capsule 10’s
Acidity, Heartburn, Gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome
Medicinal Benefits
Neksium D 40 Capsule 10’s is a combination of two drugs: Esomeprazole and Domperidone. Neksium D 40 Capsule 10’s is used to treat acidity, heartburn, gastro-oesophageal reflux disease (GERD), Zollinger-Ellison syndrome, nausea, vomiting, dyspepsia (indigestion), epigastric pain, peptic ulcers, and eradication of helicobacter pylori infection. Esomeprazole is a proton pump inhibitor that blocks an enzyme called gastric proton pump, responsible for acid production. Domperidone is a dopamine antagonist which works by increasing the movements and contractions of stomach muscle. Together, Neksium D 40 Capsule 10’s helps in treating acidity-related problems.
Dosage
Directions for Use
Storage
Side Effects of Neksium D 40 Capsule 10’s
- Dry mouth
- Stomach pain
- Diarrhea
- Headache
- Flatulence
In-Depth Precautions and Warning
Drug Warnings
Do not take Neksium D 40 Capsule 10’s if you are allergic to any of its contents or other proton pump inhibitors (such as pantoprazole, rabeprazole, lansoprazole or omeprazole); if you are taking nelfinavir (used to treat HIV); if you have prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, and heart problems. Inform your doctor before taking Neksium D 40 Capsule 10’s if you have severe kidney, heart or liver disease, or if you are due to have Chromogranin A blood test; if you have fungal infections, heart problems or HIV infection. Talk to your doctor if you experience weight loss, problems with swallowing, stomach pain, indigestion, vomit food or blood, or if you pass black stools while taking Neksium D 40 Capsule 10’s. On long-term treatment, Neksium D 40 Capsule 10’s may cause low magnesium levels, vitamin B12 levels, and increase the risk of bone fractures; the doctor may advise regular tests for monitoring your condition. Do not take Neksium D 40 Capsule 10’s if you are pregnant or breastfeeding unless prescribed by the doctor. Neksium D 40 Capsule 10’s may cause dizziness, so drive only if you are alert. Neksium D 40 Capsule 10’s should not be given to children as safety have not been established. Avoid consuming alcohol along with Neksium D 40 Capsule 10’s as it could lead to increased drowsiness and can elevate the production of stomach acid. A prolonged intake of Neksium D 40 Capsule 10’s is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.
Drug Interactions
DRUG-DRUG INTERACTIONS: Neksium D 40 Capsule 10’s may have interaction with anti-HIV (atazanavir, nelfinavir, saquinavir, ritonavir), blood thinner (clopidogrel, warfarin), anti-fungal (ketoconazole, itraconazole, voriconazole, fluconazole), anti-cancer (erlotinib, toremifene, vandetanib, vincamine), benzodiazepine (diazepam), anti-convulsant (phenytoin), anti-platelet (Cilostazol), antacid (cisapride, dolasetron, prucalopride), immunosuppressant (tacrolimus), anti-TB (rifampicin), antibiotics (Erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine), a drug used to treat hypothyroidism (levothyroxine), anti-rheumatoid (methotrexate), anti-depressant (citalopram, escitalopram), cardiac glycoside (digoxin), anti-malarial (halofantrine), anti-psychotic (haloperidol, pimozide, sertindole), anti-allergy ( mequitazin, mizolastine), anti-arrhythmic (amiodarone, dronedarone, quinidine, disopyramide, dofetilide, sotalol), anti-hypertensives (diltiazem, verapamil).
FOOD-DRUG INTERACTIONS: Neksium D 40 Capsule 10’s may have interaction with St.John’s wort (herbal supplement used to treat depression). Avoid alcohol consumption as alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
DRUG-DISEASE INTERACTION: Neksium D 40 Capsule 10’s may have interactions with Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, prolactinoma (tumour of the pituitary gland), blockage in intestines, bleeding in stomach or intestine, moderate to severe liver disease, low level of potassium or magnesium or high levels of magnesium, and heart problems.
