INTRODUCTION
MOXIGRAM contains Moxifloxacin which belongs to a group of antibiotics known as fluoroquinolones which works by killing bacteria that cause infections. It is used to treat infections of the eye (conjunctivitis) when caused by bacteria.
Moxifloxacin is a sterile ophthalmic, 8-methoxy fluoroquinolone anti-infective for topical ophthalmic use. The antibacterial action of moxifloxacin results from inhibition of the topoisomerase II (DNA gyrase) and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division. It provides prolonged contact with ocular surface that ensures longer duration of action.
Always use MOXIGRAM exactly as directed by your doctor. Before using this medicine, inform your doctor if you have eye diseases or infection, are pregnant or breastfeeding. Your doctor will prescribe the right dose depends on your child’s age and body weight. The common side effects are eye pain or irritation. Do not wear contact lenses if you have signs and symptoms of eye infection.
USES OF MOXIGRAM
- Treats infections of the eye (conjunctivitis)
HOW MOXIGRAM WORKS
MOXIGRAM works by stopping the growth of bacteria. It binds and inhibits the bacterial enzymes DNA gyrase (topoisomerase II) and topoisomerase IV, results in inhibition of DNA replication, repair and cell death.
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DIRECTIONS FOR USE
Always use MOXIGRAM exactly as your doctor has told you. Instill 1 drop in the affected eyes 3 times a day. It is for topical ophthalmic use only.
- Wash your hands and twist off the cap
- Hold the medicine, pointing down between your thumb and fingers
- Tilt your head back
- Pull down your eyelid with a clean finger, until there is a pocket between the eyelid and your eye
- Bring the bottle tip close to the eye
- Do not touch eye or eyelid, surrounding areas or other surfaces with the dropper
- Press the bottom to release one drop of medicine at a time
- After using, press a finger into the corner of your eye, by the nose for 2 – 3 minutes
- Wash your hands after use
SIDE EFFECTS OF MOXIGRAM
SERIOUS
- Swelling of the hands, feet, ankles, face, lips, mouth or throat which may cause difficulty in swallowing or breathing
- Rash or hives, large fluid – filled blisters
- Sores and ulceration
COMMON
- Eye pain or irritation
RARE
- Corneal disorder
- Blurred or reduced vision
- Inflammation or infection of the conjunctiva
- Eye strain or swelling
- Vomiting
- Nose discomfort
- Feeling of a lump in the throat
- Decreased iron in blood
- Abnormal liver blood tests and skin sensation
HOW TO MANAGE SIDE EFFECTS
Eye pain or irritation:
Place a cool compress over the eyes, by soaking cloth in warm or cold water and then squeezing it out.
Vomiting:
Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.
WARNING & PRECAUTIONS
PREGNANCY
MOXIGRAM should be used with caution in pregnant women. Consult your doctor before using.
BREASTFEEDING
MOXIGRAM should be used with caution during breastfeeding. Consult your doctor before using.
DRIVING AND USING MACHINES
Do not drive or handle any machines while using this medicine, since it may cause blurred vision.
ALLERGY
Tell your doctor if you are allergic (hypersensitive) to Moxifloxacin.
OTHERS
Inform your doctor if you have or had,
- Problems with tendons
INTERACTIONS
Inform your doctor if you are using or have recently taken any other medicines, including medicines obtained without a prescription.
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