Macprox DP 500 Tablet
Macprox DP 500 Tablet is a combination medication, primarily prescribed for the treatment and prevention of migraine attack. This medication is comprized of two drugs, Naproxen and Domperidone, which belongs to the class of a non-steroidal anti-inflammatory drugs and dopamine antagonists, respectively.
On using this medicine some side effects like stomach upset, nausea, vomiting, heartburn, drowsiness, headache may occur. Serious side effects may include easy bruising or bleeding, painful swallowing, ringing in the ears, signs of kidney problems, mood changes, unusual tiredness, swelling of the ankles, feet and hands, unexplained stiff neck, unexplained weight gain and vision changes.
To ensure this medicine is safe for you tell your doctor if you have asthma, blood disorders, nasal polyps, liver disease, heart disease, stroke, high blood pressure or throat, stomach or intestinal problems.
Take this medicine by mouth as instructed by your doctor, usually 2 or 3 times in a day. Remember to not lie down for a minimum of 10 minutes after taking it. To prevent stomach upset, take this drug with milk, food or an antacid.
To reduce your risk of side effects, start the medication at the lowest effective dose for a short period of time. Take a higher dosage if needed, after consulting with a doctor.
This medication can be used in below-mentioned conditions
Prevention Of Migraine Attacks
This medication can cause following side effects such as
Dryness In Mouth
Are there any missed dose instructions?
Take the missed dose as soon as possible but skip it if almost the time for next scheduled dose.
Are there any overdose instructions?
Consult your doctor in case of an overdose of this medication.
This medication is a combination of Naproxen and Domperidone. This medicine is prescribed for the treatment of migraine attacks. As both the drugs belong to two different classes, namely, NSAIDs (Non-Steroidal Anti Inflammatory Drug) and Dopamine antagonist, respectively, thus it works via dual mechanism.
Firstly it inhibits prostaglandin synthesis by non selectively impeding the COX -1 and COX -2 enzymes. This helps in alleviating inflammation, as prostaglandin is a regulator for inflammation in muscles. Secondly, it gets attached to the dopaminergic receptors without causing any release of the chemical dopamine. This, in turn, eases gastric emptying and abate small bowel transit time.