Lefno-20 Tablet
Lefno-20 Tablet 10’s belongs to the group of medicines called ‘anti-rheumatic agents‘ used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Rheumatoid arthritis is an auto-immune disease (body’s immune system attacks its tissue) which leads to joint pain and damage. Psoriatic arthritis is a kind of inflammatory arthritis which occurs in patients with psoriasis (red patches of skin with silvery scales).
Lefno-20 Tablet 10’s contains ‘Leflunomide’ an isoxazole immunomodulatory agent which works by blocking the formation of genetic material, i.e. DNA required for survival of replicating (dividing) cells of the immune system. As a result, it suppresses the activated immune system to reduce pain, inflammation and swelling.
Take Lefno-20 Tablet 10’s with or without food. Do not break, or chew the tablet; swallow it as a whole with a glass of water. Take Lefno-20 Tablet 10’s at the same time every day as prescribed by your doctor. In some cases, you may experience certain common side-effects such as diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
To treat your condition effectually, continue taking Lefno-20 Tablet 10’s for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take Lefno-20 Tablet 10’s if you are pregnant or planning for pregnancy as Lefno-20 Tablet 10’s causes serious congenital disabilities. Lefno-20 Tablet 10’s should not be taken by breastfeeding mothers as it passes into breast milk. Lefno-20 Tablet 10’s causes dizziness, so drive with caution. Avoid consuming alcohol along with Lefno-20 Tablet 10’s as it could lead to increased dizziness and liver damage. Lefno-20 Tablet 10’s may make you more susceptible to infections; consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising. Let your doctor before taking any live vaccines while using Lefno-20 Tablet 10’s.
Uses of Lefno-20 Tablet 10’s
Rheumatoid arthritis, Psoriatic arthritis
Medicinal Benefits
Lefno-20 Tablet 10’s belongs to the group of medicines called anti-rheumatic agents used to relieve symptoms of rheumatoid arthritis and psoriatic arthritis. Lefno-20 Tablet 10’s is a disease-modifying antirheumatic drug (DMARDs) which works by blocking part of your activated immune system and proteins that cause pain and inflammation at the damaged site. It also reduces overall flares up developed due to provoked immune system. Thus, together it helps to perform your daily activity in a better manner.
Directions for Use
Storage
Side Effects of Lefno-20 Tablet 10’s
Like all medicines, Lefno-20 Tablet 10’s can also cause side-effects, although not everybody experiences them. Diarrhoea, nausea, stomach pain, indigestion, rash, and hair loss are the common side-effects of Lefno-20 Tablet 10’s. Please consult your doctor if you experience any of these side-effects persistently.
In-Depth Precautions and Warning
Drug Warnings
Do not take Lefno-20 Tablet 10’s if you are allergic to leflunomide, have liver problems, kidney problems, low levels of protein in the blood, immune system problems, bone marrow problems, or serious infections. Lefno-20 Tablet 10’s is not recommended to be used in pregnant women, lactating mothers and people below 18 years of age. Talk to your doctor before taking Lefno-20 Tablet 10’s if you have/had serious infections like interstitial lung disease (inflammation of lungs), tuberculosis (TB), or pneumonia. Lefno-20 Tablet 10’s causes dizziness, so drive with caution. Lefno-20 Tablet 10’s may make you more susceptible to infections, and you may develop infections, sore throat, breathlessness, jaundice, unexplained bleeding or bruising. Notify the doctor if you experience these symptoms. Regular blood tests are also necessary to monitor blood cells and liver function.
Drug Interactions
DRUG-DRUG INTERACTIONS: Lefno-20 Tablet 10’s may have interaction with ibuprofen, naproxen, acetaminophen, aspirin (used to relieve pain), duloxetine (used to treat depression), prednisone (used to treat inflammation), celecoxib, azathioprine, etanercept, adalimumab, meloxicam, methotrexate, abatacept, infliximab (used to treat arthritis), and hydroxychloroquine (used to treat malaria).
FOOD-DRUG INTERACTIONS: Avoid consuming alcohol along with Lefno-20 Tablet 10’s as it could lead to liver damage.
DRUG-DISEASE INTERACTION: Lefno-20 Tablet 10’s should not be given in patients with low immunity, pneumonia, tuberculosis (TB), hypertension (high blood pressure), lung toxicity, peripheral neuropathy (nerve damage), liver and kidney dysfunction.
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