INTRODUCTION
AMBRICAN 5MG contains Ambrisentan which belongs to a group of medicines called other antihypertensives. It is used to treat pulmonary arterial hypertension (PAH). PAH is high blood pressure in the blood vessels (the pulmonary arteries) that carry blood from the heart to the lungs. It widens the pulmonary arteries, making it easier for the heart to pump blood through them. This lowers the blood pressure and relieves the symptoms. It may also be used in combination with other medicines used to treat PAH.
Take AMBRICAN 5MG according to the dose and frequency as advised by your doctor. Swallow it as a whole. Do not chew, crush or break the medicine. Do not drive or operate machinery while taking this medicine, since it may cause low blood pressure, dizziness, tiredness. This medicine is not recommended for children and adolescents under 18 years of age. Do not take this medicine if you are pregnant or breastfeeding. The common side effects of this medicine are rash, itching and swelling, low blood pressure, stuffy nose, inflamed nasal passages, headache, fast heartbeat, nausea, diarrhea and constipation.
USES OF AMBRICAN 5MG
- Treats Pulmonary arterial hypertension (PAH)
HOW AMBRICAN 5MG WORKS
AMBRICAN 5MG works by stopping the action of endothelin, a natural substance that causes blood vessels to narrow and prevents normal blood flow in people who have PAH.
DIRECTIONS FOR USE
Take this medicine according to the dose and frequency as advised by your doctor. Swallow it as a whole. Do not chew, crush or break the medicine. It may be taken with or without food.
SIDE EFFECTS OF AMBRICAN 5MG
SERIOUS
- Swelling all over the body
- Decreased sperm count
- Low red blood cell levels (anemia)
COMMON
- Rash, itching and swelling
- Swelling especially of the ankles and feet
- Light-headedness (low blood pressure)
- Flushing
- Stuffy nose
- Inflamed nasal passages
- Headache
- Fast heartbeat
- Nausea
- Diarrhoea
- Constipation
HOW TO MANAGE SIDE EFFECTS
Diarrhoea:
Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.
Nausea:
Stick to simple meals and do not eat rich or spicy foods.
Constipation:
Add fruits, vegetables whole grains and other high-fiber foods to your diet.
WARNING & PRECAUTIONS
PREGNANCY
AMBRICAN 5MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
AMBRICAN 5MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate machinery while taking this medicine, since it may cause low blood pressure, dizziness, tiredness.
KIDNEY
AMBRICAN 5MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
LIVER
AMBRICAN 5MG is not recommended in patients with active liver diseases. Consult your doctor for advice.
ALLERGY
Do not take if you are allergic (hypersensitive) to Ambrisentan or any ingredients of this medicine.
HEART DISEASE
AMBRICAN 5MG should be used with caution in patients suffering from active heart diseases. Consult your doctor for advice.
OTHERS
Tell your doctor if you had or have a condition such as:
- Scarring of the lungs
- Anaemia
- Swelling in the hands, ankles or feet caused by fluid (peripheral oedema)
- Pulmonary veno-occlusive disease
INTERACTIONS
Tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription or the following:
- Cyclosporine A
- Rifampicin
- Iloprost, epoprostenol, sildenafil
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