What is Actilyse 20mg Injection
Alteplase is used for treating blood clots in the lungs. It is also used to improve heart function and survival following a heart attack. It is also used to improve recovery and reduce disability in certain patients who have had a stroke. It may also be used for other conditions as determined by your doctor.
How does Alteplase work:
Alteplase is a tissue plasminogen activator (tPA). It works by helping to break down unwanted blood clots.
How should Alteplase be used:
How to use alteplase:
Use alteplase as directed by your doctor.
Alteplase is given as an injection at your doctor’s office, hospital, or clinic.
Common side effects of Alteplase :
No COMMON side effects have been reported with alteplase. Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); change in color of your fingers or toes; changes in vision; chest pain or pressure; confusion; fainting; one-sided weakness; purple skin color; severe dizziness or headache; severe muscle aches or pain; severe stomach pain; speech problems or changes; symptoms of bleeding (eg, vomiting blood or vomit that looks like coffee grounds; coughing up blood; blood in the urine; black, red, or tarry stools; bleeding from the gums; unusual vaginal bleeding; bruises without a reason or that get bigger; any bleeding that is severe or that you cannot stop); symptoms of kidney problems (eg, not able to pass urine, change in how much urine is passed, blood in the urine, a big weight gain); symptoms of pancreatitis (eg, severe stomach or back pain, with or without nausea or vomiting).
What do I do if I miss a dose
If you miss a dose of alteplase, contact your doctor right away.
What precautions should I take when taking Alteplase :
Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have had a recent surgery or procedure or if you have recently had a baby
if you have a disease of the blood vessels in your brain; recent bleeding of the stomach, bowel, genitals, or urinary tract; a recent injury; high blood pressure; inflammation around the heart; inflammation inside the heart due to an infection; blood problems, including blood clotting problems; liver or kidney problems; bleeding in the eye due to diabetes or other problems; a serious infection; or blood vessel inflammation
if you have an increased risk of a blood clot in your heart
Tell your doctor or dentist that you take alteplase before you receive any medical or dental care, emergency care, or surgery.
Serious and sometimes fatal bleeding problems have happened with alteplase. Discuss any questions or concerns with your doctor.
You may bleed more easily. Avoid activities that may cause bruising or injury. Tell your doctor if you have unusual bruising or bleeding. Tell your doctor if you have dark, tarry, or bloody stools.
Lab tests may be performed while you use alteplase. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Use alteplase with caution in the ELDERLY; they may be more sensitive to its effects.
When do I need to seek medical help
Do NOT use alteplase if:
you are allergic to any ingredient in alteplase
you have active internal bleeding, history of stroke, recent brain or spinal surgery (within 3 months), a growth in the brain, abnormal formation of blood vessels, or a certain type of bulging blood vessel (aneurysm)
you have a heart attack or blood clot in the lung and you also have had recent brain or spinal injury, a history of bleeding problems, or severe uncontrolled high blood pressure
you have a stroke and you also have known or suspected bleeding in the head or brain, a history of bleeding in the brain, a recent serious head injury, uncontrolled high blood pressure, low platelet count, high international normalized ratio (INR) or prothrombin time, or a history of bleeding problems, or if you had a seizure at the onset of the stroke
you have a stroke and you are taking warfarin, or you have used heparin within the past 48 hours and you currently have a high activated partial thromboplastin time.
Can I take Alteplase with other medicines:
Some medicines may interact with alteplase. Tell your health care provider if you are taking any of the following medicines.
Abciximab, anticoagulants (eg, warfarin, heparin), antiplatelet medicine (eg, clopidogrel), aspirin, or dipyridamole because the risk of bleeding may be increased
Angiotensin-converting enzyme (ACE) inhibitors (eg, lisinopril) because the risk of serious side effects, such as severe swelling or trouble breathing, may be increased
Nitrates (eg, nitroglycerin, isosorbide dinitrate) because the effectiveness of alteplase may be decreased.
How do I store Alteplase :
Alteplase is handled and stored by a health care provider. You will not store it at home. Keep all medicines out of the reach of children and away from pets.
Pregnancy Category
Pregnancy Category:C
If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using alteplase while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use alteplase, check with your doctor. Discuss any possible risks to your baby.
Therapeutic Classification
Fibrinolytics & Thrombolytics
Reviews
There are no reviews yet.