Twinblok Trio Tablet (Chlorthalidone )

Overview

Twinblok Trio ER Tablet is used for Hypertension, Edema, Angina pectoris, Heart failure and other conditions. Twinblok Trio ER Tablet may also be used for purposes not listed in this medication guide.

Twinblok Trio ER Tablet contains Chlorthalidone, Cilnidipine and Metoprolol Succinate as active ingredients.
Twinblok Trio ER Tablet works by increasing elimination of sodium and chloride and therefore water from the body; suppressing the beta 2-adrenoreceptors activity; possessing the beta-blocking activity; blocking the activity of calcium channels in the blood vessels to reduce blood pressure;
Detailed information related to Twinblok Trio ER Tablet’s uses, composition, dosage, side effects and reviews is listed below.

Uses

Twinblok Trio ER Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
Hypertension
Edema
Angina pectoris
Heart failure

Dosage

Twinblok Trio Tablet
Twinblok-T 40 Tablet
Twinblok 10 Tablet
Twinblok 5mg Tablet

Side-effects

The following is a list of possible side-effects that may occur from all constituting ingredients of Twinblok Trio ER Tablet. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
Gastrointestinal disturbances
Abnormally high level of glucose in urine
Gastric pain
Abnormal liver function
Yellowing of skin
Eyes
Low blood magnesium level
Impotence
High blood glucose level
Nausea
Vomiting
Abnormal blood counts
Low blood pressure with change in position
Pale red rash
Itchy skin
Loose motion
Low potassium in blood
Abnormally high level of uric acid in blood
Sensitivity to sunlight
Difficulty in passing stool
Worsening of diabetic metabolic state
Loss of appetite
Dizziness
High blood sodium level
Rise in blood lipid level
Gastrointestinal disturbance
Hearing loss
Acute saline depletion
Allergic manifestations
Carbohydrate intolerance
Postural
Hypotension
Jaundice
Cardiac arrhythmias
Fatigue
Tiredness
Shortness of breath
Bradycardia
Palpitations
Congestive heart failure
Peripheral edema
Wheezing
Dry mouth
Constipation
Flatulence
Digestive tract disorders
Heartburn
Diarrhea
Rash
Headache
Flushing
Twinblok Trio ER Tablet may also cause side-effects not listed here.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.

Precautions

Before using Twinblok Trio ER Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
Allergies
Asthma
Avoid drinking alcohol
Avoid getting dehydrated during exercise and in hot weather
Consult your doctor in case of existing fluid and electrolyte disturbances, hepatic cirrhosis, severe heart failure, hyperuricemia, mild to moderate renal impairment
Discontinue in case of ischemic pain following administration
Do not stop taking drug suddenly in case of angina
Do not take chlorthalidone and potassium salt or a potassium sparing diuretic
Exercise caution in case of kidney or liver disease and diabetes
Liver disease

Interactions with Twinblok Trio ER Tablet

If you use other drugs or over the counter products at the same time, the effects of Twinblok Trio ER Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Twinblok Trio ER Tablet may interact with the following drugs and products:
Aldesleukin
Amiodarone
Antihypertensive drugs
Antipsychotic drugs
Asfurosemide
Bisacodyl
Bumetanide
Carbamazepine
Cimetidine
Clonidine

When not to use Twinblok Trio ER Tablet

Hypersensitivity to Twinblok Trio ER Tablet is a contraindication. In addition, Twinblok Trio ER Tablet should not be used if you have the following conditions:
Acute myocardial infarction
Cardiac ischemia
Hypersensitivity
Lack of urine production
Preexisting heart conditions
Sulfa allergy
Unstable angina
cardiogenic shock
decompensated cardiac failure
heart block greater than first degree

Composition and Active Ingredients

Twinblok Trio ER Tablet is composed of the following active ingredients (salts)
Chlorthalidone – 12.5mg
Metoprolol Succinate – 50mg
Cilnidipine – 10mg