Medical Description
Tenepride M 500 tablet is an anti-diabetic medicine. It is used to lower the high blood sugar levels in people with type 2 diabetes mellitus along with lifestyle changes. Tenepride M 500mg tablet is a combination medicine containing teneligliptin and metformin as its main components. This medicine works best when used along with a healthy diet and regular exercise. This medicine will help you keep your sugar levels in control and reduce the risk of diabetes complications. Thus, always take Tenepride M 500mg tablet as prescribed by your doctor, and at the same time to gain optimal benefit. Do not stop taking this medicine abruptly, it may lead to serious health consequences. You may experience the most common side effects such as diarrhoea, nausea, vomiting, upset stomach, headache, low blood sugar level (hypoglycemia). If these side effects worsen reach out to the nearest clinic. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding and about all the medicines and supplements you take and all the conditions or diseases you suffer from, before starting Tenepride M 500mg tablet.
Uses of Tenepride M 500mg Tablet
Tenepride M 500 tablet is used to treat type 2 diabetes mellitus along with an appropriate diet and exercise.
Contraindications of Tenepride M 500mg Tablet
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If you are allergic to Teneligliptin, Metformin or any of the ingredient of Tenepride M 500 tablet.
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If you have liver or severe kidney problems.
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If you are an alcoholic.
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If you are in a state of diabetic coma due to a sudden rise or drop in blood sugar level.
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If you have type1 diabetes mellitus.
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If you have a severe infection or you have a recent surgery.
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If you have a known history of pancreatitis.
Side effects of Tenepride M 500mg Tablet
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Low blood sugar level, be watchful for symptoms of low blood sugar like trembling, sweating, anxiety, blurred vision, tingling lips, paleness, irritability or confusion
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Nausea
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Constipation
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Stomach pain
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Flatulence (gas), polyps in stomach
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Diarrhoea, loss of appetite
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Rashes, itching, allergy
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Tiredness
Precautions and Warnings of Tenepride M 500mg Tablet
Pregnancy
Q:
Can I take Tenepride M 500 tablet during pregnancy?
A:There is limited information about the effect of Tenepride M 500 tablet in pregnancy. Thus, it should be only used, if prescribed by your doctor after assessing the need and benefits. Talk to your doctor if you are pregnant or think you may be pregnant.
Breast Feeding
Q:Can I take Tenepride M 500 tablet while breastfeeding?
A:Component of Tenepride M 500 tablet passes into the breastmilk, thus consult a doctor before using it while breastfeeding.
Driving
Q:
Can I drive if I have consumed Tenepride M 500 tablet?
A:After taking Tenepride M 500 tablet, there are chances your blood sugar can fall. You may experience faintness, confusion and increased sweating. So, it would be best if you take extra care when driving. Keep a juice or chocolate handy while driving and in case you start experiencing any of these symptoms, immediately have it.
Alcohol
Q:
Can I consume alcohol with Tenepride M 500mg tablet?
A:
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Alcohol lowers blood sugar which can be dangerous and also increases the risk of a serious condition called lactic acidosis.
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Alcohol can also increase the risk of developing the serious side effect of pancreatitis.
Other General Warnings
Talk to your doctor if
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You have a known history of pancreatitis or develop sudden pain in the stomach or back, immediately stop this medicine and report to the hospital.
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You have a liver or heart problem like irregular heartbeat and heart failure.
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You are suffering from persistent diarrhoea, vomiting and loss of body fluids.
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You have serious liver and kidney function problems.
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You have an irregular diet, habit of excessive alcohol intake and intense exercise.
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You have a history of any abdomen surgery.
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You are using other medicines like Glimepiride because it can cause a drop in blood sugar level.
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You experience muscle pain, stomach pain, vomiting, breathing difficulty and low body temperature. It could be a serious condition known as lactic acidosis.
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Tenepride M 500 tablet should not be used in children below 18 years of age.
Mode of Action of Tenepride M 500mg Tablet
How Does It Work?
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Tenepride M 500 tablet works by the combined effect of both its components – Teneligliptin & Metformin.
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Teneligliptin works by increasing insulin secretion from the pancreas by inhibiting the enzyme dipeptidyl peptidase 4 (DPP4), whereas Metformin decreases the production of glucose from the liver, the amount of glucose absorbed from the intestine and increases insulin sensitivity.
Directions for Use of Tenepride M 500 mg Tablet
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Tenepride M 500 tablet should be taken as directed by your doctor.
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Swallow it whole with a glass of water, do not cut, break or chew the medicine.
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It should be taken with or after a meal to reduce its side effects.
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It would be best if you took it at a fixed time for optimal results.
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You should not consume it more than that prescribed by your doctor.
Interactions of Tenepride M 500mg Tablet
Interactions with other medicines
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If you need to take an injection of iodine-containing contrast medium into your bloodstream, for an X-ray or scan, your doctor will ask you to stop taking this medicine before or at the time of injection.
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You may have symptoms of low blood sugar if you are taking other medicines for diabetes like Metformin, Insulin, Canagliflozin and Liraglutide.
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Medicines used to treat depression like Phenelzine.
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Medicines for fever and pain (salicylates like aspirin).
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Medicines used to treat high blood pressure like Atenolol, Propranolol and Verapamil.
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You may have high blood sugar if you are taking steroids, thyroxine.
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Never take this medicine if you are taking medicines like Quinidine, Sotalol, Procainamide and Amiodarone as it may cause heart rhythm problems and cardiac arrest.
Interactions with food items
Absorption of vitamin B12 appears to be reduced during long-term Metformin therapy and annual screening of serum vitamin B12 levels and red blood cell parameters has been recommended.
Storage and disposal of Tenepride M 500mg Tablet
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Store Tenepride M 500 tablets below 25°C.
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Keep it out of reach of children and pets.
Dosage of Tenepride M 500 mg Tablet
Overdose
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Excess of Tenepride M 500 tablet may cause lactic acidosis characterized by vomiting, stomach and muscle cramps, difficulty in breathing.
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If you think you have taken too much of this medicine contact your doctor immediately or visit the nearest hospital.
Missed a Dose
If you missed a dose of Tenepride M 500 tablet, take it as soon as you remember. If it’s time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose of this medicine to compensate for the missed one.
