INTRODUCTION
SILOFAST contains silodosin which belongs to the group of medicines called selective alpha-1 adrenergic receptor antagonist. It is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia in men. Benign prostate hyperplasia (BPH) is a non-cancerous enlargement of the prostate gland in men. Symptoms of Benign prostate hyperplasia (BPH) may include difficulty in urination, urinary frequency and an inability to complete bladder emptying.
Silodosin blocks the alpha-1 adrenoreceptors present in tissues of human prostate and bladder and relax the smooth muscle in these tissues, resulting in improvement of symptoms of BPH. The side effect occurs most commonly while taking this medicine is an orgasm with reduced or no semen. This side effect is reversible with discontinuation of the product. Silodosin can cause postural hypotension, with or without dizziness, so do not drive, operating machinery, or perform any hazardous tasks while taking this medicine if you feel so.
Always take this medicine as directed by your physician. Swallow the medicine as a whole with water and do not crush or chew the medicine. Do not take this medicine if you are suffering from any kidney disease or liver disease. Consult your doctor before taking. Your doctor will decide the correct dose for you depending upon your medical condition and response to treatment. To get the most benefit, try taking this medication regularly with the same meal each day.
USES OF SILOFAST
- Treat signs and symptoms of benign prostatic hyperplasia in men
HOW SILOFAST WORKS
Silodosin works by blocking the alpha-1 adrenoreceptors where the smooth muscle in these tissues relax, resulting in an improvement in urine flow and a reduction in symptoms of benign prostatic hyperplasia.
DIRECTIONS FOR USE
Always take this medicine as directed by your physician. Swallow the medicine as a whole with water and do not crush or chew the medicine. Your doctor will decide the correct dose for you depending upon your medical condition and response to treatment. To get the most benefit, try taking this medication regularly with the same meal each day.
SIDE EFFECTS OF SILOFAST
COMMON
- Dizziness
- Headache
- Diarrhea
- Orthostatic hypotension (fainting while getting up)
- Abnormal ejaculation or
- Stuffy nose, sinus pain
HOW TO MANAGE SIDE EFFECTS
Diarrhea:
Drink lots of fluids to avoid dehydration. Avoid taking any other medicines for diarrhoea without speaking to a doctor.
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Dizziness:
Lie down and close your eyes. Drink plenty of water and take rest. If still dizziness persists, consult your physician.
WARNING & PRECAUTIONS
DRIVING AND USING MACHINES
Do not drive or operate any machinery because this medicine will make you feel dizzy.
ALCOHOL
Avoid consumption of alcohol while taking this medicine, because it may make you feel dizzier.
KIDNEY
SILOFAST should be taken with caution in patients with severe kidney disease. Consult your doctor for advice.
LIVER
SILOFAST should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
ALLERGY
Do not take this medicine if you are allergic (hypersensitive) to silodosin.
OTHERS
Before taking this medicine, inform your doctor if you have or ever had low blood pressure, prostate cancer or undergoing a cataract surgery.
INTERACTIONS
Talk to your doctor, if you are taking,
- Medicines used to treat infections (e.g. clarithromycin, telithromycin, itraconazole, ketoconazole, posaconazole or voriconazole)
- Medicines used to treat heart problems (nicardipine, quinidine, digoxin)
- Medicine used to treat viral infection like hepatitis C or HIV/AIDS
- Medicine used to treat impotence or erectile dysfunction (e.g. tadalafil, sildenafil)
- Other medicines similar to silodosin (e.g. alfuzosin, doxazosin, prazosin, tamsulosin, or terazosin)
- Cyclosporine (used to reduce graft rejection)
- Imatinib (used to treat certain type of blood cancer)
- Isoniazid (used to treat tuberculosis)
- Nefazodone (used to treat depression)
