Rolazin Tablet ER (Ranolazine 500mg)
Rolazin 500 Mg Tablet is used to relieve chest pain in conditions like chronic angina. Proper lifestyle modifications are necessary along with this medicine for a speedy recovery. Elderly and low body weight patients should use this medicine with caution due to the increased risk of undesired effects.
Substitutes
List of substitutes for Rolazin 500 Mg Tablet
Cartinex 500 Mg Tablet
Micro Labs Ltd.
Corvela 500 Mg Tablet
Cipla Ltd.
Ranoplan 500 Mg Tablet
Mankind Pharmaceuticals Ltd.
Razona 500 Mg Tablet
Cadila Pharmaceuticals Ltd.
Synx 500 Mg Tablet
Alembic Ltd.
Side effects
Major & minor side effects for Rolazin 500 Mg Tablet
Dizziness
Ringing or buzzing in the ears
Chest tightness
Headache
Blurred vision
Constipation
Dry mouth
Stomach pain
Loss of strength
Uses of Rolazin 500 Mg Tablet
What is it prescribed for?
Angina Pectoris
This medicine is used for the treatment of chronic angina pectoris (severe chest pain) caused due to reduced flow of blood and oxygen to the heart. It is not recommended as first-line therapy for treating acute angina attacks.
When not to use?
Severe liver disease
This medicine is contraindicated in patients suffering from kidney diseases due to the increased risk of severe adverse effects.
Drug interaction
This medicine is not recommended for use in patients receiving strong CYP3A inhibitors like ketoconazole, clarithromycin, nelfinavir, and CYP3A inducers like carbamazepine, phenobarbital, phenytoin, rifampin, etc. due to the increased risk of worsening severe adverse effects.
Allergy
This medicine is not recommended for use if you have a known history of allergy to ranolazine or any other inactive ingredients present in the formulation.
Warnings
Warnings for special population
Pregnancy
Rolazin medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings
Elderly population
This medicine should be used with caution in patients more than 60 years of age due to an increase in the risk of undesired effects. Close monitoring of kidney function is necessary. The dose should be adjusted based on the kidney function.
Low body weight
This medicine should be used with caution in patients less than 60 kg of body weight due to an increase in the risk of undesired effects. The dose should be adjusted based on body weight.
Use in children
This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.
Driving or operating machinery
This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
Dosage
Missed Dose
The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already the time for your next scheduled dose.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Metformin
Phenytoin
Digoxin
Atorvastatin
Disease interactions
Liver Disease
This medicine should be used with extreme caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of the liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Kidney disease
This medicine should be used with caution in patients with kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
QT Prolongation
This medicine should be used with caution in patients with a history of prolonged QT interval and patients using medicines that prolong QT interval. Appropriate dose adjustments should be made under your doctor’s supervision.
Food interactions
Consumption of grapefruit juice while taking this medicine is not recommended due to an increase in the risk of dizziness, fast heartbeat, and fainting. Any such symptoms should be reported to the doctor on priority.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
General Instructions
Take this medicine as advised by the doctor. Do not consume larger quantities than prescribed. It is advised that you inform the doctor if you have a history of liver or kidney disease. Proper lifestyle modifications should be adopted along with the medicine to prevent further complications. Report to the doctor if you experience any undesired effects while receiving the medicine.
