INTRODUCTION
PRAMIROL 0.125MG contain Pramipexole dihydrochloride which belongs to a group of medicine called dopamine agonists. Stimulation of the dopamine receptors triggers nerve impulses in the brain that help to control body movements. It is used to treat the symptoms of primary Parkinson’s disease in adults. It can be used alone or in combination with levodopa (another medicine for Parkinson’s disease). It works by increasing the action of dopamine, a chemical messenger that is needed to control movement in the brain.
Parkinson’s disease is a disorder of the central nervous system that affects movement, often including tremors. Nerve cell damage in the brain causes dopamine levels to drop, leading to the symptoms of Parkinson’s. Parkinson’s often starts with a tremor in one hand. Other symptoms are slow movement, stiffness, and loss of balance.
Always take PRAMIROL 0.125MG exactly as your doctor has told you. This medicine must be taken with or without food. The most common side effects are dizziness, nausea, hallucinations, sleeplessness (insomnia), peripheral oedema, constipation, vomiting and headache. This medicine is strictly not recommended for use in children and adolescents under 18 years. Before taking this medicine tell your doctor if you have ever had kidney disease, heart disease, liver problems. Pregnant and breastfeeding women should consult their doctor before taking this medicine.
USES OF PRAMIROL 0.125MG
- Treat the symptoms of primary Parkinson’s disease in adults
HOW PRAMIROL 0.125MG WORKS
PRAMIROL 0.125MG works by increasing the action of dopamine, a chemical messenger that is needed to control movement in the brain.
DIRECTIONS FOR USE
Always take PRAMIROL 0.125MG exactly as your doctor has told you. This medicine must be taken with or without food. Try to take this medicine at the same time each day. It should be swallowed whole with water. Do not crush or chew the medicine.
SIDE EFFECTS OF PRAMIROL 0.125MG
COMMON
- Dyskinesia
- Dizziness, tiredness, confusion
- Nausea
- Urge to behave in an unusual way
- Hallucinations
- Sleeplessness (insomnia)
- Peripheral oedema
- Headache
- Hypotension
- Abnormal dreams
- Constipation
- Visual impairment
- Vomiting
- Weight loss including decreased appetite
RARE
- Mania
HOW TO MANAGE SIDE EFFECTS
Dizziness:
Get up and move around to feel awake, take small naps to edge off the sleepiness. Give your eyes a break to avoid fatigue and eat a healthy food to boost energy.
Nausea:
Try taking this medicine with, or just after, a meal or snack and stick to simple meals and do not eat rich or spicy food.
Headache:
Apply hot or cold-water bag on your head. Take rest in a quiet and dark room. Drink tea or coffee.
Constipation:
Take fibre rich foods such as fresh fruit, vegetables and cereals, and drink plenty of water. Exercise more regularly.
WARNING & PRECAUTIONS
PREGNANCY
PRAMIROL 0.125MG is not recommended for use in pregnant women unless necessary. Discuss the risks and benefits with your doctor.
BREASTFEEDING
PRAMIROL 0.125MG is not recommended for use in breastfeeding women unless necessary. Discuss the risks and benefits with your doctor.
DRIVING AND USING MACHINES
Do not drive or operate any machine while taking this medicine since it may cause hallucinations, sleepiness.
ALCOHOL
Consumption of alcohol is not recommended during treatment with PRAMIROL 0.125MG.
KIDNEY
PRAMIROL 0.125MG should be used with caution in patients suffering from active kidney diseases. Consult your doctor for advice.
LIVER
PRAMIROL 0.125MG should be used with caution in patients suffering from liver function impairment or active liver diseases.
ALLERGY
Do not take PRAMIROL 0.125MG if you are allergic (hypersensitive) to Pramipexole dihydrochloride or any other ingredients in this medicine.
HEART DISEASE
PRAMIROL 0.125MG should be used with caution in patients suffering from active heart disease. Consult your doctor for advice.
OTHERS
Tell your doctor if you have or had a condition such as,
- Hallucinations (seeing, hearing, or feeling things that are not there)
- Dyskinesia (e.g. abnormal, uncontrolled movements of the limbs)
- Have advanced Parkinson’s disease
- Dystonia, axial dystonia (inability of keeping your body and neck straight and upright)
- Experience forward flexion of the head and neck (also called antecollis), forward bending of the lower back (also called camptocormia) or sidewards bending of the back (also called pleurothotonus or Pisa Syndrome)
- Sleepiness and episodes of suddenly falling asleep
- Psychosis (e.g. comparable with symptoms of schizophrenia)
- Vision impairment
INTERACTIONS
Talk to your doctor if you are taking,
- Cimetidine (used to treat excess stomach acid and stomach ulcers)
- Amantadine (used to treat Parkinson’s disease)
- Mexiletine (used to treat irregular heartbeats)
- Zidovudine (used to treat AIDS)
- Cisplatin (used to treat various types of cancers)
- Quinine (used to prevent painful night-time leg cramps and for the treatment of a type of malaria known as falciparum malaria (malignant malaria))
- Procainamide (used to treat irregular heartbeat)
- Levodopa
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