Pio-M 15 Tablet
Pio-M (500/15 mg) Tablet is a combination medicine used to control high blood glucose levels in patients with type 2 diabetes mellitus. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.
Side effects
Major & minor side effects for Pio-M (500/15 mg) Tablet
Nausea and Vomiting
Diarrhea
Abdominal pain
Hypoglycemia
Lactic Acidosis
Weakness
Chest discomfort
Headache
Runny Nose
Belching and Heartburn
Swelling of face, lips, eyelids, tongue, hands and feet
Weight gain
Uses of Pio-M (500/15 mg) Tablet
What is it prescribed for?
Type II Diabetes Mellitus
This medicine is used along with an appropriate diet and exercise regimen to reduce blood glucose levels in patients with type 2 diabetes.
When not to use?
Severe kidney impairment
This medicine is not recommended for use in patients with a severe impairment of kidney function due to the increased risk of serious adverse effects.
Allergy
This medicine is not recommended for use in patients with a known allergy to pioglitazone, metformin, or any other inactive ingredients present along with these medicines.
Metabolic Acidosis
This medicine is not recommended for use in patients with metabolic acidosis since it may worsen the patient’s condition.
Heart Failure
This medicine is not recommended for use in patients with a history of heart failure since it may worsen the patient’s condition.
Related Product
Pio-M 15 Tablet
Pio-M 30 Tablet
Warnings
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings
Kidney diseases
This medicine should be used with caution in patients with a known history of kidney disease due to the increased risk of worsening of the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Stress
Use of this medicine should be discontinued in patients exposed to stressful conditions such as a fever, trauma, surgeries, or accidents since it may not be effective in controlling blood sugar levels in these conditions. Replacement with a suitable alternative should be considered under your doctor’s supervision.
Type 1 diabetes
This medicine is not recommended for use in patients suffering from Type I diabetes since it is not effective in treating such patients.
Diarrhea
This medicine may cause diarrhea when therapy is initiated. In most cases, diarrhea subsides by itself. Contact your doctor if the problem persists for longer durations. Therapy may need to be discontinued in some cases based on the clinical condition.
Cardiovascular diseases
This medicine should be used with extreme caution in patients with a known history of cardiovascular diseases due to the increased risk of worsening of the patient’s condition. Report any unusual symptoms to the doctor immediately. Close monitoring of heart function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Liver diseases
This medicine should be used with caution in patients with a known history of liver disease due to the increased risk of worsening of the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Edema
This medicine should be used with caution in patients with edema due to the increased risk of worsening of the patient’s condition.
Ovulation
This medicine should be used with caution due to the increased chances of ovulation in premenopausal anovulatory women. Adequate contraceptive measures are recommended for such patients to avoid an unplanned pregnancy.
Fractures
This medicine may increase the risk of fractures in some patients. This risk is especially higher in female patients. Close monitoring of bone health is recommended during treatment with this medicine. Replacement with a suitable alternative may be required based on the clinical condition.
Pediatric Use
This medicine is not recommended for use in children and adolescents.
Antidiabetic agents
This medicine should be used with caution in patients taking other antidiabetic agents due to the increased risk of very low blood glucose levels. Close monitoring of blood glucose levels and appropriate dose adjustments may be required based on the clinical condition.
Dosage
Missed Dose
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
Interactions
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.
Interaction with Medicine
Amlodipine
Estradiol
Gatifloxacin
Ketoconazole
Gemfibrozil
Iodinated Contrast Media
Aloe Vera
Insulin injection
Disease interactions
Lactic Acidosis
This medicine may cause lactic acidosis in some patients. This risk is especially higher in patients with kidney diseases, heart diseases, or septicemia. Close monitoring of blood glucose levels, kidney function, heart function, and liver function may be required for such patients based on the clinical condition. Report any symptoms such as fatigue, breathing difficulty, increased sleep, nausea, vomiting, diarrhea, irregular heartbeat, etc. to the doctor immediately. Appropriate corrective measures and discontinuation of therapy may be required in some cases based on the clinical condition.
Vitamin B12 deficiency
This medicine should be used with extreme caution in patients with vitamin B12 deficiency since it may worsen the patient’s condition. Appropriate vitamin B12 supplementation and dose adjustments may be required based on the clinical condition.
Congestive heart failure
This medicine is not recommended for use in patients with a known history of congestive heart failure due to the increased risk of fluid retention and worsening of the heart failure.
Bladder cancer
Use of this medicine is not recommended in patients having an active bladder tumor since it may worsen the patient’s condition.
Liver Disease
This medicine should be used with extreme caution in patients with a known history of liver impairment due to the increased risk of adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Anemia
This medicine is not recommended for use in patients suffering from anemia since it may worsen the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
General Instructions
Take this medicine as instructed by your doctor. It is advised to take this medicine with meals. Your dose is likely to change over time based on therapeutic response and clinical condition. Regular monitoring of blood sugar levels is recommended during treatment with this medicine. You should always carry a sugar candy with you to counteract unexpected lowering of blood sugar levels. Do not change the dose or duration of use without consulting your doctor. This medicine will show better results if you maintain a strict exercise and diet regimen. Consult the doctor if you experience any undesirable side effects.
