Pacroma Cream (Pimecrolimus) 

About Pacroma 1% Cream 10 gm

Pacroma 1% Cream 10 gm belongs to a class of dermatological preparation called ‘immunosuppressants‘ primarily used to prevent allergies including swelling, itching redness, heat and pain caused due to certain skin problems such as dermatitis (itchy, swelling of the skin) and eczema (itchy, cracked, swollen or rough skin). Eczema is a condition in which skin patches become inflamed, itchy, cracked and rough. Dermatitis is a skin condition that causes itchy, dry skin or a rash on swollen, reddened skin.

Pacroma 1% Cream 10 gm contains Pimecrolimus works by stopping the immune system from producing chemical substances that may cause eczema. When the skin reacts to any type of allergens, such chemicals substances are released normally. It acts inside the skin cells that cause the inflammation and characteristic redness and itching of eczema. Pacroma 1% Cream 10 gm is used to treat swelling, itching redness, heat, and pain caused due to skin problems such as eczema or atopic dermatitis (itchy, cracked, swollen or rough skin).

Pacroma 1% Cream 10 gm is available in the form of topical (skin use) cream. Your doctor will advise the appropriate dose depending on your medical condition. Avoid contact of Pacroma 1% Cream 10 gm with nose, mouth, or eyes. In case Pacroma 1% Cream 10 gm comes in contact with these areas accidentally, rinse with water thoroughly. Common side effects of Pacroma 1% Cream 10 gm include burning, irritation, itching, and redness at the application site. Most of these side effects of Pacroma 1% Cream 10 gm do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Pacroma1% Cream 10 gm or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Pacroma 1% Cream 10 gm. Do not use Pacroma 1% Cream 10 gm in more than prescribed doses, or for a prolonged time as it may cause adverse effects. Avoid consuming alcohol while using Pacroma 1% Cream 10 gm. It can make your skin (particularly on your face) become flushed or red, and feel hot. If you have a weakened immune system (immunocompromised), have erythroderma (redness of almost the entire body), or a skin condition called Netherton’s syndrome (a disorder that affects the skin, hair, and immune system) and skin malignancies (tumours), and skin infections (including chickenpox or herpes), inform your doctor before starting Pacroma 1% Cream 10 gm.

Uses of Pacroma 1% Cream 10 gm

Atopic dermatitis (eczema)

Medicinal Benefits

Pacroma 1% Cream 10 gm contains Pimecrolimus is a class of medications called topical calcineurin inhibitors with anti-inflammatory properties, specifically treats inflammation of the skin called atopic dermatitis (eczema). It works by stopping the immune system from producing chemical substances that may cause eczema. When the skin reacts to any type of allergens, such chemicals substances are released normally. It acts inside the skin cells that cause the inflammation and characteristic redness and itching of eczema. Pacroma1% Cream 10 gm is used to treat swelling, itching redness, heat, and pain caused due to certain skin problems such as eczema or atopic dermatitis (itchy, cracked, swollen, or rough skin) in children (aged 2 years and above), teenagers, and adults. When used to treat early signs and symptoms Pacroma 1% Cream 10 gm can prevent progression to severe flare-ups.

Directions for Use

Pacroma 1% Cream 10 gm is only for external use. Take a small amount of Pacroma 1% Cream 10 gm on the fingertip and apply as a thin layer on the clean and dry affected area as prescribed by your doctor. Avoid contact of Pacroma 1% Cream 10 gm with nose, mouth or eyes. In case Pacroma 1% Cream 10 gm comes in contact with these areas accidentally, rinse with water thoroughly. Wash your hands before and after using Pacroma1% Cream 10 gm if hands are not the affected area to prevent the spread of infection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Pacroma 1% Cream 10 gm

• Mild irritation
• Skin redness
• Burning sensation at the site of application

In-Depth Precautions and Warning

Drug Warnings

Do not use Pacroma1% Cream 10 gm to areas of the skin affected by an active viral infection such as cold sores (herpes simplex) or chickenpox. Pacroma 1% Cream 10 gm may be associated with an increased risk of severe herpes simplex skin infection (eczema herpeticum). Therefore if you develop painful sores anywhere on your body, tell your doctor immediately. If you are pregnant or a nursing mother, it is advised to consult a doctor before using Pacroma 1% Cream 10 gm. Pacroma 1% Cream 10 gm is not recommended for children below 2 years of age. Avoid using Pacroma 1% Cream 10 gm on open wounds, windburned, sunburned, irritated, or dry skin. Do not cover or wrap the treated area with a bandage unless advised by your doctor as it may cause harmful effects. Avoid contact of topical Pacroma 1% Cream 10 gm with nose, mouth, or eyes as it may irritate. In case Pacroma 1% Cream 10 gm comes in contact with these areas accidentally, rinse with water thoroughly. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) that is in contact with Pacroma 1% Cream 10 gm catches fire and burns easily.  If you have a weakened immune system (immunocompromised), have erythroderma (redness of almost the entire body), or a skin condition called Netherton’s syndrome (a disorder that affects the skin, hair, and immune system), and skin malignancies (tumours), please inform your doctor before starting Pacroma 1% Cream 10 gm. Avoid excessive exposure to sunlight, sun lamps, and tanning beds while using Pacroma 1% Cream 10 gm. If you are outdoors after applying Pacroma 1% Cream 10 gm, wear loose-fitting clothing, appropriate sunscreen, and minimise the amount of time you spend in the sun.

Drug Interactions

Drug-Drug Interaction: Pacroma1% Cream 10 gm may interact with antifungals (fluconazole, itraconazole, ketoconazole), calcium channel blockers (diltiazem, verapamil) antiulcer (cimetidine) antibiotics (clarithromycin, erythromycin, troleandomycin,  metronidazole),  androgenic hormones (danazol),  immunosuppressant  (cyclosporine), HIV protease inhibitors (indinavir, ritonavir, delavirdine), anti-TB (isoniazid), an antidepressant (nefazodone, fluoxetine, fluvoxamine), oral contraceptives (birth control pills).

Drug-Food Interaction: Pacroma1% Cream 10 gm may interact with alcohol. Therefore, avoid the consumption of alcohol with Pacroma 1% Cream 10 gm.

Drug-Disease Interaction: If you have skin areas that have cancers or pre-cancers, Netherton’s syndrome, skin infections (including chickenpox or herpes), or a weak immune system, inform your doctor before taking Pacroma1% Cream 10 gm.