Novastat Gold 20 Capsule (Aspirin/Rosuvastatin/Clopidogrel)

INTRODUCTION

NOVASTAT GOLD 20MG is a combination of Aspirin, Clopidogrel and Rosuvastatin which belongs to the group of medicines called Non-Steroidal Anti-Inflammatory Drugs, Antiplatelets and HMG-CoA reductase inhibitors respectively. NOVASTAT GOLD 20MG is indicated for the treatment of acute coronary syndrome, myocardial infarction (heart attack), angina (chest pain), or stroke (reduced blood supply to brain leading to brain death) that were caused due to clot or plaque formation in the blood vessels supplying the heart. Acute coronary syndrome is a heart condition caused by plaque rupture or clot formation in the coronary arteries. Symptoms include heart attack, chest pressure or pain while at rest, shortness of breath and sweating.

Clopidogrel is an antiplatelet medicine that blocks the aggregation of platelets (cells that form blood clots) in the blood vessels and aspirin is a non-steroidal anti-inflammatory drug that irreversibly inhibits the activity of certain enzymes involved in the production of platelets. Rosuvastatin is an HMG-CoA reductase inhibitor that helps in reducing the production of bad cholesterol. Collectively they reduce the risk of clot or plaque formation in the blood vessels suppling the heart, leading to an improved cardiac function.  Along treatment with NOVASTAT GOLD 20MG follow a healthy low-fat diet as advised by doctor to achieve better results.

Avoid drinking alcohol during the therapy, as it could increase the risk of bleeding in the gastrointestinal tract. NOVASTAT GOLD 20MG is not recommended for use in patients having severe liver, kidney, or heart disease. Consult your doctor before taking. NOVASTAT GOLD 20MG is generally not recommended for use in pregnant or breastfeeding women and in children (below 18 years). Consult your doctor for an alternative therapy. The most common side effects of taking NOVASTAT GOLD 20MG are increased bleeding tendency, nausea, indigestion, diarrhea, stomach pain, constipation, muscle pain, dizziness, and headache. Contact your doctor if any of these symptoms worsen.

USES OF NOVASTAT GOLD 20MG

• Treats acute coronary syndrome
• Treats myocardial infarction
• Treats angina
• Treats stroke

HOW NOVASTAT GOLD 20MG WORKS

NOVASTAT GOLD 20MG effectively improves cardiac function and reduces the risk of heart problems, where clopidogrel acts by inhibiting platelet aggregation in the coronary arteries, aspirin acts by blocking the actions of an enzyme called cyclo-oxygenase 1 which is believed to be responsible for catalyzing the synthesis of platelets and rosuvastatin acts by inhibiting the action of an enzyme called HMG-CoA reductase, which is required to catalyze the formation of cholesterol, thus preventing clot or plaque formation in the coronary arteries leading to an uninterrupted supply of oxygen and blood to the heart.

DIRECTIONS FOR USE

Take NOVASTAT GOLD 20MG as advised by your physician. Swallow NOVASTAT GOLD 20MG with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF NOVASTAT GOLD 20MG

HOW TO MANAGE SIDE EFFECTS

Nausea and vomiting:

Try to take NOVASTAT GOLD 20 MG with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if the symptom did not improve.

Diarrhea:

Drink lots of fluids, such as water or fruit juices to keep yourself hydrated. Avoid taking any medicine on your own for treating diarrhea. Consult your doctor if the symptom did not improve.

Headache:  

Rest and relax. Drink plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the head if required. Do not consume too much of alcohol. Consult your doctor if the symptom did not improve.

Dizziness:

Try to rest and relax. Get enough sleep. Avoid driving or operating any tools or machines while you are feeling dizzy. Do not consume too much of alcohol, as it can aggravate your dizziness. Consult your doctor if the symptom did not improve.

Constipation:

Eat fiber rich foods such as fresh fruits, vegetables and cereals and drink plenty of water. Try to exercise more regularly. Consult your doctor if the symptom did not improve on its own.

Stomach pain:

Rest and relax. Eat and drink slowly or try to have smaller and frequent meals. Keep a heat pad on your stomach. Do not self-treat on your own and consult your doctor if the symptom did not improve on its own.

WARNING & PRECAUTIONS

INTERACTIONS

A. Drug-Drug interactions:

Before taking NOVASTAT GOLD 20MG inform to your doctor, if you are taking any of these medicines:

• Other anticoagulants (used for blood thinning) Ex. warfarin, coumarin, heparin, phenindione
• Other cholesterol-lowering medicines (Ex. clofibrate, gemfibrozil, fenofibrate, ezetimibe)
• Other non-steroidal anti-inflammatory drugs (Ex. ibuprofen, paracetamol)
• Medicines used to treat HIV infection (Ex. ritonavir with lopinavir and/or atazanavir or sofosbuvir with velpatasvir and voxilaprevir)
• Selective serotonin reuptake inhibitors (used to treat depression) Ex. fluoxetine, sertraline, paroxetine, or fluvoxamine
• Medicines used to treat stomach ulcers such as antacids (Ex. aluminium hydroxide, magnesium hydroxide) and proton-pump inhibitors (Ex. omeprazole or esomeprazole)
• Medicines used during percutaneous coronary intervention (Ex. abciximab, eptifibatide, and tirofiban)
• Antibiotics (used to treat bacterial infections) such as macrolides (Ex. azithromycin, erythromycin, roxithromycin, and clarithromycin) or fusidic acid
• Medicines used to treat epilepsy (Ex. phenytoin, valproic acid)
• Medicines used to treat diabetes (Ex. insulin, glipizide, glimepiride)
• Ciclosporin or tacrolimus (used to prevent graft rejection or treat auto-immune disease)
• Nicotinic acid (used to treat vitamin b3 deficiency)
• Azole antifungal agents (used to treat fungal infection) Ex. clotrimazole, fluconazole
• Methotrexate (used to treat cancer or other auto-immune diseases)
• Digoxin (used to treat abnormal heart rate)
• Darolutamide (used to treat prostate cancer)
• Regorafenib (used to treat colon or rectal cancer)
• Probenecid or sulfinpyrazone (used to treat gout)
• Dipyridamole (an antiplatelet medicine)
• Lithium (used to treat metal illness)
• Corticosteroids (used to treat pain and inflammation) Ex. prednisolone, dexamethasone
• Acetazolamide (used to treat or prevent altitude sickness)
• Mifepristone (abortion pill)
• Metoclopramide (used to treat vomiting)

Overdosage:

If you or anyone else take too much of NOVASTAT GOLD 20MG, contact your doctor immediately or go to a hospital straight away. Overdosage symptoms of NOVASTAT GOLD 20MG might include increased bleeding, confusion, disorientation, coma, convulsions, vomiting, tinnitus (ringing in the ears), vertigo (spinning sensation), sweating, warm extremities with bounding pulses, increased respiratory rate and hyperventilation.