Norpregalin Tablet (Pregabalin 75mg/Nortriptyline 10mg)

Norpregalin Tablet

Norpregalin tablet is composed of Pregabalin and Nortriptyline. It is an anticonvulsant and is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia. It is used for the treatment of diabetic nerve pain, epilepsy, spinal cord injury, restless leg syndrome and generalised anxiety disorder.This medication works by binding to a certain region of the brain and reducing the pain signals sent out by the damaged nerves of the body.

Ensure your doctor is informed if you have any of the following medical conditions before starting the medication:

If you have congestive heart failure, irregular heartbeat, diabetes, bleeding problems, muscle problems, highballed pressure or low platelet count.
If you have improper kidney functioning or are on dialysis.
If you have a history of angioedema.
If you are pregnant, planning to be pregnant or are breastfeeding.
If you take any other medicines, dietary supplements or herbal preparations.
If you have mental or mood problems, suicidal thoughts, or are dealing with depression.

Use

The medication can treat the below provided problems:

Peripheral Neuropathy

Postherpetic Neuralgia

Side Effects

A patient can suffer from the following side effects:

Dizziness

Drowsiness

Peripheral Edema

Nausea

Blurred Vision

Dry Mouth

Weight Gain

Work

This medication is a combination of Pregabalin and Nortriptyline, thus work through a dual mechanism of action. Primarily, it behaves as a GABA analogue and binds to the voltage-gated calcium channels in the central nervous system. This causes a reduced release of neurotransmitters like serotonin, dopamine, substance P thus slowing down nerve signals. Secondarily, it blocks the serotonin reuptake at the neuronal membrane. Also, it inhibits the reuptake of norepinephrine and raises its concentration in the synaptic cleft.

Dosage

Are there any missed dose instructions?

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped.
Are there any overdose instructions?

Contact your doctor immediately if an overdose is suspected.