MARZON DUO 750MG TABLET (SULTAMICILLIN TOSILATE)

INTRODUCTION

MARZON DUO contains Sultamicillin which belongs to a group of medicines called beta-lactamase inhibitors. It is indicated to treat upper respiratory tract infections including sinusitis, otitis media and tonsillitis, lower respiratory tract infections including bacterial pneumonias and bronchitis, urinary tract infections, pyelonephritis, skin and soft tissue infections and gonococcal infections. It may also be indicated in patients requiring sulbactam/ampicillin therapy following initial treatment with sulbactam/ampicillin IM/IV.

Sultamicillin is a codrug of ampicillin and sulbactam. After oral administration, it is absorbed and hydrolytically cleaved to ampicillin and sulbactam by enzymes in the gut wall. It is a semi-synthetic orally active broad-spectrum penicillin antibiotic, exerts antibacterial activity against sensitive organisms by inhibiting biosynthesis of cell wall mucopeptide. Sulbactam is a beta-lactamase inhibitor, irreversibly inhibits many beta-lactamases which occur in resistant bacteria strains.

Always take MARZON DUO exactly as directed by your doctor. Tell your physician if you have liver, kidney or heart problems, pregnant women and breastfeeding mothers. Your physician will give the right dose depends on your child’s age and body weight. The common side effects are vomiting, headache, nausea and diarrhoea.

USES OF MARZON DUO

• Treats upper respiratory tract infections including sinusitis, otitis media and tonsillitis, lower respiratory tract infections including bacterial pneumonias and bronchitis, urinary tract infections, pyelonephritis, skin and soft tissue infections and gonococcal infections

HOW MARZON DUO WORKS

MARZON DUO works by killing the bacteria by preventing them from forming the bacterial protective covering which has enhanced activity against bacteria and less antibiotic resistance.

DIRECTIONS FOR USE

Always take MARZON DUO exactly as your doctor has told you. Swallow as whole, with a glass of water. Do not crush or chew. It can be taken with or without food.

SIDE EFFECTS OF MARZON DUO

HOW TO MANAGE SIDE EFFECTS

Headache:

Rest and drink plenty of fluids. Ask your doctor to recommend a painkiller.

Nausea:

Stick to simple normal meals and do not eat rich or spicy foods.

Diarrhoea:

Drink more fluids to avoid dehydration. ORS should be used to prevent dehydration.

Vomiting:

Drink clear or ice-cold drinks and take light, bland foods and avoid fried and sweet foods.

Abdominal pain:

Place a warm water bottle on abdomen or soak in a warm bath. Drink plenty of clear fluids and water.

WARNING & PRECAUTIONS

INTERACTIONS

Tell your doctor if you are taking,

• Allopurinol
• Anticoagulants
• Chloramphenicol, erythromycin, sulfonamides and tetracyclines
• Estrogen-containing oral contraceptives
• Methotrexate
• Probenecid