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MACIKAD TAB 10TAB
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Home New Products Macikad 10mg Tablet (Macitentan 10mg)
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Macikad 10mg Tablet (Macitentan 10mg)

$92.00 – $320.00

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Country of Origin

india

Dosage Form

Tablets

Generic Name

Macitentan

Indication

Pulmonary arterial hypertension (PAH)

Packaging

10 tablets in 1 strip

Manufacturer

Lupin Ltd

Composition

Macitentan (10mg)

Macikad 10mg Tablet (Macitentan 10mg)
Pack Size Price Price/Unit Add To Cart
10 Tablet/s $92.00 $9.2
20 Tablet/s $175.00 $8.75
40 Tablet/s $320.00 $8
SKU: 6298 Category: New Products
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Description

Macikad 10mg Tablet (Macitentan 10mg):

A medication known as Macikad 10mg Tablet, which contains the active component macitentan, is available. The most common indication for the use of macitentan as a medication is for the treatment of pulmonary arterial hypertension (PAH), which refers to a condition in which the arteries of the lungs have abnormally high blood pressure. Endothelin is a substance that causes blood vessels to narrow and become more constrictive. This medication is an endothelin receptor antagonist, which belongs to a class of drugs known as endothelin receptor antagonists. Endothelin receptor antagonists work by blocking the effects of endothelin.

Mechanism of Action

Antagonising endothelin receptors in a selective manner is how macitentan achieves its therapeutic effects in the body. It does this by inhibiting the action of endothelin, which results in the blood vessels in the lungs relaxing and expanding, which in turn lowers the blood pressure that is elevated in the pulmonary arteries. This results in increased blood flow and oxygenation of the lungs, which alleviates the symptoms that are associated with PAH.

Indications

Macikad 10mg Tablet is indicated for the treatment of pulmonary arterial hypertension (PAH) in adult patients to improve exercise capacity and delay clinical worsening. Patients should take one tablet twice daily with meals. Either as a stand-alone treatment or in conjunction with other PAH-targeted medicines, such as phosphodiesterase type 5 inhibitors or prostacyclin analogues, are both viable applications for its utilisation.

Dosage and Administration

One tablet (10 milligrammes) of Macikad 10 mg Tablet should be taken orally once daily, either with or without food. This is the recommended dose. It is important to take the tablet as directed, without crushing or chewing it. It is critical to take the medication at the same time each day if you want to keep the concentration of the drug in the body stable. It is possible to modify the dosage in accordance with the individual patient’s response and level of tolerance.

Contraindications

The use of the Macikad 10mg Tablet is not recommended for patients who have been shown to have an extreme sensitivity to macitentan or any of the other components of the tablet. Since it has been demonstrated that macitentan is harmful to developing foetuses, it should not be used in pregnant women. In addition, the Macikad 10mg Tablet should not be co-administered with potent inhibitors of cytochrome P450 3A4 and P-glycoprotein, as doing so may lead to an increase in the plasma concentration of the drug macitentan.

Warnings and Precautions

Because macitentan can cause hepatotoxicity, medical professionals should carefully evaluate patients for preexisting liver disease before beginning treatment with Macikad 10mg Tablet. During treatment, patients should have their liver function monitored on a regular basis. Macitentan has also been linked to a drop in haemoglobin levels, which can necessitate adjustments to the prescribed dosage or even blood transfusions. Patients need to be informed of the risks of potential fluid retention as well as edoema, and appropriate management strategies need to be put into place.

Drug Interactions

It is possible for Macikad 10mg Tablet to interact with other medications or substances, which could change how well they work or raise the risk that they will cause adverse effects. It is imperative that you provide your primary care physician with information regarding any and all medications, whether they be prescribed, purchased over the counter, or herbal in nature, that you are currently taking. There is a possibility that macitentan will interact with medications that are powerful inducers or inhibitors of cytochrome P450 3A4 and P-glycoprotein. Some examples of these medications include rifampicin, ketoconazole, and clarithromycin.

Adverse Reactions

Headaches, nasal congestion, flushing, peripheral edoema, anaemia, and infections of the upper respiratory tract are common adverse reactions associated with the use of Macikad 10mg Tablet. Hypersensitivity reactions, liver toxicity, and other adverse reactions that occur less frequently but have the potential to be life-threatening are also possible side effects. It is imperative to seek immediate medical attention in the event that any of these adverse reactions occur or continue after initial treatment.

Conclusion

The medication known as Macikad 10mg Tablet (Macitentan 10mg) is prescribed to patients who have been diagnosed with pulmonary arterial hypertension (PAH). It accomplishes this by acting selectively as an endothelin receptor antagonist, which results in a relaxation and widening of the blood vessels in the lungs. This results in an increase in blood flow and a decrease in blood pressure. The Macikad 10 mg Tablet is generally well tolerated; however, medical professionals should monitor patients for the possibility of adverse reactions and routinely evaluate liver function while patients are taking the medication. It is extremely important to take this medication exactly as directed, including in terms of the dosage and administration instructions. If you have any concerns or questions about this medication, you should speak with a medical professional.

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