Kombiglyze XR 5mg/500mg Tablet
Kombiglyze XR 5mg/500mg Tablet 7’s belongs to a group of medicines known as’antidiabetics’, used in the treatment of type 2 diabetes in adults. Kombiglyze XR 5mg/500mg Tablet 7’s is prescribed for the condition of type 2 diabetes when diet and exercise alone cannot control their blood sugar levels. It is the first-line therapy for patients with type 2 diabetes that restores the body’s response to insulin. Insulin is the hormone that controls sugar levels in your blood. People with type 2 diabetes either do not produce enough insulin or the insulin produced is unable to perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes, so it is also known as adult-onset diabetes.
Kombiglyze XR 5mg/500mg Tablet 7’s contains two medications namely: Saxagliptin and Metformin. Saxagliptin work by blocking the action of DPP-4- dipeptidyl peptidase-4 (an enzyme which destroys hormone ‘Incretin’). The enzyme ‘Incretins’ help to produce more insulin only when required and reduce blood sugar level produced by the liver when not needed. On the other hand, Metformin, which is a ‘biguanide’, acts by lowering the liver’s glucose production, delaying glucose absorption from intestines, and increasing the body’s response to insulin. In a nutshell, the two medicines together prevent the blood glucose levels from rising to very high levels, thus keeping your Diabetes under control.
Take Kombiglyze XR 5mg/500mg Tablet 7’s as prescribed by your doctor. You are suggested to take $ame as long as your doctor has prescribed it after checking your medical condition. The most common side effect of Kombiglyze XR 5mg/500mg Tablet 7’s is hypoglycemia (low blood glucose levels), upper respiratory tract infection, nasopharyngitis (infection of nose and throat with common cold), and headache.
Kombiglyze XR 5mg/500mg Tablet 7’s should not be stopped even if you feel better, without consulting your doctor as sugar level keeps changing. If you stop taking Kombiglyze XR 5mg/500mg Tablet 7’s abruptly, it may increase your sugar levels which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy). Kombiglyze XR 5mg/500mg Tablet 7’s should not be taken if you have severe kidney or liver disease. Please inform your doctor if you have any heart disease, is or planning to get pregnant or breastfeeding. Safety and efficacy of Kombiglyze XR 5mg/500mg Tablet 7’s in children under 18 years have not been established, so it should not be given to them. Patients taking digoxin (a heart medicine) with Kombiglyze XR 5mg/500mg Tablet 7’s should be closely monitored as severe drug interaction has been observed.
Uses of Kombiglyze XR 5mg/500mg Tablet 7’s
Type 2 diabetes (non-insulin-dependent diabetes).
Medicinal Benefits
Kombiglyze XR 5mg/500mg Tablet 7’s contains two medications namely: Saxagliptin and Metformin. Kombiglyze XR 5mg/500mg Tablet 7’s act together to keep your blood sugar levels under check. The strict control of blood sugars is essential to mention the many disabling side effects of Diabetes. Kombiglyze XR 5mg/500mg Tablet 7’s shows optimum effects when taken along with healthy lifestyle changes like weight loss, regular exercise, healthy diet, etc. Kombiglyze XR 5mg/500mg Tablet 7’s should not be used in patients with type 1 diabetes and for the treatment of diabetic ketoacidosis. Thus, Kombiglyze XR 5mg/500mg Tablet 7’s plays a vital role in controlling blood sugar levels and prevents serious complications of diabetes like eyesight loss (retinopathy), kidney (nephropathy), nerve damage (neuropathy), diabetic foot ulcer, and delayed wound healing.
Related Product
Kombiglyze XR 5mg/1000mg Tablet
Kombiglyze XR 5mg/500mg Tablet
Directions for Use
Storage
Side Effects of Kombiglyze XR 5mg/500mg Tablet 7’s
- Dizziness
- Sweating
- Palpitations
- hunger pangs
- Dry mouth and skin
- Hypoglycaemia (low blood glucose level)
In-Depth Precautions and Warning
Drug Warnings
A prolonged intake of Kombiglyze XR 5mg/500mg Tablet 7’s may cause acute pancreatitis (swollen pancreas), and critical kidney problem. Increased risk of hypoglycemia (low blood sugar level) can occur when Kombiglyze XR 5mg/500mg Tablet 7’s is added to other anti-diabetic agents or insulin therapy. In this case, your doctor may adjust the dose of Kombiglyze XR 5mg/500mg Tablet 7’s. Severe allergic reactions might occur in some patients taking Kombiglyze XR 5mg/500mg Tablet 7’s like anaphylaxis, angioedema (swelling under the skin), and exfoliative skin conditions including Stevens-Johnson syndrome.
Drug Interactions
Drug-Drug Interaction: Kombiglyze XR 5mg/500mg Tablet 7’s interacts with an anti-depressant (bupropion), drugs used to treat glaucoma, antibiotics (cephalexin, ciprofloxacin), anti-acidity drugs (cimetidine), heart condition drugs (digoxin), anti-HIV drugs (dolutegravir), ethanol, saliva reducing drugs (glycopyrrolate), iodinated X-ray contrast agents, anti-epileptic drugs (topiramate, lamotrigine), heart-related chest medicine (ranolazine). Other drug interactions can contribute to an increased low blood sugar including sex hormones (androgens), anti-oxidant (alpha-lipoic acid), painkillers (aspirin), anti TB drugs (prothionamide), growth hormones (pegvisomant), and other antidiabetic medicines.
Drug-Food Interaction: Intake of excessive alcoholic beverages may increase the chance of a life-threatening condition known as Lactic Acidosis. So, avoid intake of alcoholic beverages with Kombiglyze XR 5mg/500mg Tablet 7’s.
Drug-Disease Interaction: Kombiglyze XR 5mg/500mg Tablet 7’s should be used with caution in patients with a history of pancreatitis/pancreatic disease and renal dysfunction.
