The ISTamet 50mg/500mg Tablet is a powerful prescription medication formulated to help control high blood sugar levels in adults with Type 2 Diabetes Mellitus. It combines two effective anti-diabetic agents—Sitagliptin (50mg) and Metformin (500mg)—that work synergistically to improve blood glucose regulation. This innovative combination not only enhances insulin secretion but also reduces glucose production in the liver, providing dual-action control for diabetic patients.

As a Superintendent Pharmacist in the USA, I can confidently say that ISTamet 50mg/500mg Tablet is a trusted and clinically proven therapy for Type 2 diabetes management. It is widely recommended by healthcare professionals to help patients maintain long-term glycemic stability while minimizing the risk of hypoglycemia.

Composition and Active Ingredients(Sitagliptin 50mg + Metformin 500mg)

Each ISTamet 50mg/500mg Tablet contains two potent active ingredients:

• Sitagliptin (50mg): A DPP-4 inhibitor that enhances the body’s natural ability to lower blood sugar levels after meals.
• Metformin (500mg): A biguanide that reduces glucose production in the liver and improves insulin sensitivity.

This combination provides comprehensive diabetes control by targeting different mechanisms of glucose metabolism.

How ISTamet 50mg/500mg Tablet Works

The ISTamet 50mg/500mg Tablet acts through a dual mechanism to regulate blood sugar levels effectively:

• Sitagliptin enhances the action of incretin hormones, which stimulate the pancreas to release more insulin and reduce the amount of glucose produced by the liver.
• Metformin improves peripheral glucose uptake and utilization while inhibiting hepatic glucose production.
• Together, these two components ensure better postprandial (after-meal) and fasting blood sugar control.

Benefits of ISTamet 50mg/500mg Tablet

• Dual Mechanism of Action: Combines the benefits of Sitagliptin and Metformin for optimal glucose control.
• Reduces Insulin Resistance: Helps the body utilize insulin more efficiently.
• Supports Weight Management: Unlike some other diabetes medications, it generally does not cause weight gain.
• Lowers HbA1c Levels: Demonstrated to reduce long-term blood glucose (HbA1c) effectively.
• Improves Quality of Life: Reduces the risk of diabetes-related complications such as neuropathy, nephropathy, and retinopathy.
• Convenient Dosing: Once or twice-daily dosing depending on medical advice makes it easy to incorporate into daily routines.

The ISTamet 50mg/500mg Tablet offers long-term glycemic control and is especially beneficial for patients who are not adequately controlled with metformin alone.

Directions for Use

• Take ISTamet 50mg/500mg Tablet exactly as prescribed by your doctor.
• Swallow the tablet whole with a glass of water—do not crush or chew.
• It is best taken with food to reduce gastrointestinal side effects associated with metformin.
• Regular blood sugar monitoring is essential to track progress.
• Do not stop or change the dosage without consulting your physician.

Possible Side Effects

While ISTamet 50mg/500mg Tablet is well-tolerated, some individuals may experience mild side effects such as:

• Nausea or stomach discomfort
• Diarrhea or gas
• Headache
• Dizziness
• Fatigue

Severe but rare side effects may include lactic acidosis or pancreatitis. If you experience severe abdominal pain, unusual tiredness, or difficulty breathing, seek immediate medical attention.

Precautions and Warnings

Before using ISTamet 50mg/500mg Tablet, discuss your medical history with your healthcare provider, especially if you have:

• Kidney or liver impairment
• Heart disease
• Alcohol dependence
• Vitamin B12 deficiency

Pregnant or breastfeeding women should use this medicine only under medical supervision. Avoid alcohol as it can increase the risk of lactic acidosis.

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Drug Interactions

ISTamet 50mg/500mg Tablet may interact with certain medications, including:

• Insulin or other oral anti-diabetic drugs
• Diuretics
• Corticosteroids
• Beta-blockers
• Antifungal or antibiotic agents

Always inform your doctor about all medications or supplements you are taking.

Storage Instructions

• Store ISTamet 50mg/500mg Tablet in a cool, dry place below 30°C.
• Keep away from moisture, direct sunlight, and out of reach of children.
• Do not use after the expiry date mentioned on the packaging.

Why Choose ISTamet 50mg/500mg Tablet from Us

When you order ISTamet 50mg/500mg Tablet from our pharmacy, you are choosing quality, authenticity, and expert care. Our medications are sourced directly from licensed manufacturers and are verified by professional pharmacists. We ensure:

• 100% genuine medicines
• Fast and discreet shipping
• Secure online ordering
• Pharmacist consultation and guidance
• Affordable pricing and regular discounts

Take charge of your diabetes management with ISTamet 50mg/500mg Tablet, and experience the convenience of trusted online ordering backed by professional healthcare support.