Isryl-M 3mg Tablet
Isryl-M 3mg Tablet 15’s belongs to the group of medications called ‘antidiabetic agents’ used in the treatment of Type 2 diabetes mellitus. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than normal. It occurs when the body does not produce enough insulin (metabolizes glucose), or if produced, it cannot function properly in the body.
Isryl-M 3mg Tablet 15’s is a combination of three medicines, namely: Metformin, Glimepiride, and Pioglitazone. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Glimepiride acts by increasing the amount of insulin released by the pancreas. Pioglitazone works by decreasing the amount of glucose released by the liver and also by improving the sensitivity of tissues towards insulin effects.
You should take this medicine as prescribed by your doctor. You may experience side-effects of such as nausea (feeling sick), vomiting (falling sick), diarrhea, headache, stomach ache, respiratory infection, weight gain, sweating, palpitations, and vision problems. Some patients experience decline in blood sugar levels lower than normal (hypoglycemia) resulting in sweating, dizziness, headache, confusion, feeling hungry, temporary changes in vision, uneasiness, irritability, and weakness. In such cases, seek medical attention immediately.
Do not take Isryl-M 3mg Tablet 15’s if you are allergic to any of its contents. Do not use this medicine if you have heart failure, bladder cancer, or diabetic ketoacidosis (a complication of diabetes). Isryl-M 3mg Tablet 15’s may cause ‘lactic acidosis’ (accumulation of lactic acid in the blood), which requires immediate medical attention. The risk increases if you are previously diagnosed with kidney or liver diseases. Do not consume alcohol (risk of lactic acidosis) or fast for prolonged periods (risk of hypoglycemia). Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Uses of Isryl-M 3mg Tablet 15’s
Type 2 Diabetes Mellitus
Medicinal Benefits
Isryl-M 3mg Tablet 15’s contains Metformin, Glimepiride, and Pioglitazone. Isryl-M 3mg Tablet 15’s is given when single or dual therapy of hypoglycemic agents is not effective in diabetes patients. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Glimepiride acts by increasing the secretion of insulin by the pancreas. Pioglitazone works by decreasing the amount of glucose released by the liver and improving insulin sensitivity in muscle and fat.
Directions for Use
Storage
Side Effects of Isryl-M 3mg Tablet 15’s
- Nausea (feeling sick)
- Vomiting (falling sick)
- Diarrhea
- Headache
- Stomach ache
- Respiratory infection
- Weight gain
- Sweating
- Palpitations
- Numbness
- Vision problems
In-Depth Precautions and Warning
Drug Warnings
Isryl-M 3mg Tablet 15’s should be used with caution in patients with heart diseases as it increases the risk of heart failure. Isryl-M 3mg Tablet 15’s may cause ‘lactic acidosis’ (buildup of lactic acid in the blood), characterized by abdominal pain, muscle cramps, vomiting, severe fatigue, and difficulty breathing. It is a life-threatening condition that requires immediate medical attention. Inform your doctor if you have any severe liver or kidney problems as their normal functioning is required to eliminate excess lactic acid from the body. Do not consume excess alcohol as it increases the risk of lactic acidosis. Isryl-M 3mg Tablet 15’s may lower vitamin B12 levels, so it is recommended to take blood tests regularly to identify any vitamin deficiencies.
Drug Interactions
Drug-Drug interactions: Isryl-M 3mg Tablet 15’s may have an interaction with medicines used to treat bacterial infections (rifampicin, tetracycline, and clarithromycin), a medicine used to treat fungal infections (fluconazole), other oral antidiabetics, and medicines used to treat gout (probenecid).
Drug-Food interactions: Intake of excess alcohol may increase the chance of a life-threatening condition known as lactic acidosis.
Drug-Disease interactions: Isryl-M 3mg Tablet 15’s should be avoided in patients with heart diseases (congestive heart failure and myocardial infarction), vitamin B12 deficiency, and alcoholism, type I diabetes, bladder cancer, edema (fluid retention), liver disease, premenopausal anovulation, obesity (weight gain), anemia should avoid intake of Isryl-M 3mg Tablet 15’s.
