Medical Description
Antidep 75 mg tablet is used to treat depression, a mental health condition that causes persistent feelings of sadness and loss of interest in activities once enjoyed. This medicine is also often prescribed to children as a treatment for bedwetting. The active ingredient in Antidep is imipramine. Antidep belongs to the tricyclic antidepressants (TCA) class of drugs. It works by increasing the levels of healthy mood hormones in the body and blocking some muscles’ action, which helps treat bedwetting in children. Antidep 75 mg tablets bring about specific changes in the brain’s chemical messengers, leading to an increase in the levels of hormones responsible for decreasing sadness, elevating mood, and bringing relaxation. Common side effects of Antidep 75 mg tablets include nausea, vomiting, delirium, and sleepiness. This medicine must be taken on under the supervision of a medical doctor.
Uses of Antidep 75 MG
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Antidep 75 mg tablets are used to treat:
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Depression
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Bed-wetting in children above 6 years of age
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Chronic neuropathic pain
Contraindications of Antidep 75 MG
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Do not take Antidep 75 mg tablets or take with caution:
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If you are allergic to imipramine.
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If you have liver disease.
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If you have kidney disease.
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If you have heart problems.
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If you have a respiratory disease.
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If you have a paralytic condition of the gut.
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If you have chronic constipation
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If you have glaucoma.
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If you have tumours of the adrenal gland, pheochromocytoma, and neuroblastoma.
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If you have galactose intolerance.
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If you have alcohol or drug addiction.
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If you are a child under 6 years of age.
Side effects of Antidep 75 MG
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Common side effects of Antidep 75 mg tablets:
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Nausea
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Vomiting
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Delirium
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Sleepiness
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Unsteadiness
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Convulsions
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Anxiety
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Weight gain
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Dryness of mouth
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Constipation
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Rare and serious side effects of Antidep 75 mg tablets
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Rashes or itching
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Dizziness
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Hallucination
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Confusion
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Low blood pressure
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Low body temperature
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Increased and irregular heartbeat
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Difficulty in passing urine
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Change in the pressure in eyes called glaucoma
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Sexual dysfunction
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Stiffness in the muscle
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Tremors
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Suicidal thoughts
Precautions and Warnings of Antidep 75 MG
Pregnancy
Breast Feeding
Driving
Alcohol
Other General Warnings
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You are allergic to imipramine.
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You have liver disease, kidney disease, heart problems, or breathing problems.
Mode of Action of Antidep 75 MG
How Does It Work?
Imipramine is the active ingredient in Antidep 75 mg tablets. This medicine belongs to the tricyclic antidepressants (TCA) class of drugs. It acts by increasing certain hormones in the brain, such as 5-hydroxytryptamine, serotonin, and norepinephrine. Antidep 75 mg tablets start working within a few minutes of taking it and stay in the blood for a long time. Therefore, the dose is adjusted significantly for older adults. Antidep 75 mg tablets are used to treat severe depression or when other medicines to treat this condition have not worked. Antidep 75 mg tablets work by helping elevate mood and remove sadness, anger and nervousness. This is due to the blocking effect of Antidep 75 mg tablets on a hormone responsible for the involuntary action of muscles. This helps in stopping the unintentional passing of urine during sleep in children. It is also used as part of the therapy for treating bedwetting in children above 6 or 7 years of age.
Directions for Use of Antidep 75 MG
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Use Antidep 75 mg tablets only on the advice of a doctor. They will assess your condition and recommend the dosage and the timing best suited to you. In addition, they will periodically monitor you for side effects.
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Take Antidep 75 mg tablets with or without food as its absorption is not influenced by food.
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Antidep 75 mg tablet is to be taken as a whole and not broken, chewed, or crushed.
Interactions of Antidep 75 MG
Interactions with other medicines
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Antidep 75 mg tablets may interact with the following medicines:
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Monoamine oxidase inhibitor (MAOI) antidepressants such as isocarboxazid and phenelzine
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Selective serotonin reuptake inhibitor (SSRI) antidepressants such as fluoxetine and fluvoxamine
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Central nervous system depressants such as barbiturates, benzodiazepines, or general anaesthetics
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Drugs used to reduce nervous tension such as thioridazine, thiothixene, clozapine, chlorpromazine and risperidone
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Antihypertensives such as reserpine, clonidine, guanethidine, and alpha methyldopa
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Anticholinergic agents such as phenothiazine, cetirizine, atropine, and biperiden
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Medicines used to treat Parkinson’s disease
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Sympathomimetic drugs such as adrenaline, noradrenaline, isoprenaline, phenylephrine, and phenylpropanolamine
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Painkillers like tramadol, opioids, fentanyl, ibuprofen, and ketorolac
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Calcium channel blockers like diltiazem and verapamil
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Antiarrhythmic drugs like quinidine
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Carbamazepine and phenytoin
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Oral contraceptives
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Antiviral drugs like ritonavir
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Muscle relaxants like baclofen
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Cimetidine and methylphenidate
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Disulfiram and alprazolam
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Ofloxacin and norfloxacin
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Methylene blue
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Glucagon
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Cannabis
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Nicotine
Interactions with food items
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Food doesn’t interfere with the absorption and bioavailability of Antidep 75 mg tablets. You can continue with your usual diet. However, avoid taking caffeine and tobacco.
Storage and disposal of Antidep 75 MG
Storage of this medicine requires special attention due to its toxic effects. It should be stored away from the reach of children or any possible misuse, preferably in a locked place. Store the medicine at room temperature in a cool, dry place away from heat and humidity. If there are some leftover tablets after completing the recommended course, dispose of them safely to avoid accidental usage. Do not flush in the toilet.
Dosage of Antidep 75 MG
Overdose
Symptoms of overdose include low blood pressure, excessive drowsiness, confusion, comatose condition, unsteadiness, restlessness, agitation, stiffness of muscles, convulsions, fast and irregular heartbeat, heart failure, difficulty in passing urine or stopping of urine, and breathing failure. Call for emergency services if you experience any of these symptoms.
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