Ajaduo 25mg/5mg Tablet (Empagliflozin / Linagliptin)

Introduction and Overview

Empagliflozin and linagliptin are the two active components in the combination drug Ajaduo 25mg/5mg Tablet. For the management of type 2 diabetes mellitus, it is frequently recommended. Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor, whereas Empagliflozin is a member of the class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. This combo drug functions by assisting in lowering blood sugar levels via various methods of action.

How Does Ajaduo Work?

25/5 mg of Ajaduo Tablet helps treat type 2 diabetes via two distinct mechanisms:

1. Empagliflozin: By inhibiting SGLT2 in the kidneys, empagliflozin prevents the reabsorption of glucose and promotes the excretion of extra glucose in the urine. Haemoglobin A1c (HbA1c), a marker of long-term blood sugar control, is reduced as a result, helping to lower blood sugar levels.
2. Linagliptin: Linagliptin blocks DPP-4, an enzyme that degrades incretin hormones, to produce its effects. Linagliptin raises the levels of active incretin hormones such glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) by inhibiting DPP-4. These hormones increase the release of insulin and decrease the release of glucagon, which aids in controlling blood sugar levels.

Precautions and Warnings

Prior to using Ajaduo 25mg/5mg Tablet, it’s critical to take the following safety measures into account:

1. Ajaduo may have an impact on kidney function. Your doctor may need to check your kidney function both before you start taking the medicine and on a regular basis after. Before taking Ajaduo, let your doctor know if you have any kidney issues.
2. While Ajaduo by itself typically does not result in hypoglycemia (low blood sugar), it may raise the risk when combined with other anti-diabetic drugs like insulin or sulfonylureas. It’s crucial to frequently check your blood sugar levels and be informed of the symptoms and signs of hypoglycemia.
3. Rare instances of pancreatitis (pancreatic inflammation) associated with the usage of DPP-4 inhibitors have been made. Inform your healthcare practitioner right away if you encounter severe stomach discomfort that doesn’t go away.
4. Allergies: Before beginning treatment with Ajaduo, let your doctor know if you have a known allergy to Empagliflozin, Linagliptin, or any other ingredient.

Related Product

Ajaduo 10mg/5mg Tablet
Ajaduo 25mg/5mg Tablet

Possible Side Effects

25/5 mg of Ajaduo Some people may experience negative effects from tablets. The following are typical adverse effects of Linagliptin with empagliflozin:

• infections of the urinary tract
• more frequent urination
• When used with other anti-diabetic drugs, hypoglycemia
• (Common cold) Nasopharyngitis
• Headache

Typically, these side effects are minor and go away on their own. Notify your healthcare practitioner if you develop any severe or persistent side effects for additional assessment and advice.

Additional Considerations

Here are some extra factors to take into account when using Ajaduo 25mg/5mg Tablet in addition to the information already mentioned:

1. Ajaduo contains the drug empagliflozin, which may have an impact on renal function. It’s crucial to regularly check kidney function both before starting Ajaduo and after. If you have a history of renal disease or any other kidney-related conditions, let your healthcare professional know.
2. One of Ajaduo’s main ingredients, empagliflozin, has the potential to lower blood pressure. For patients using blood pressure drugs, this effect can be more noticeable. Regularly check your blood pressure, and let your doctor know if you develop any symptoms like lightheadedness or dizziness.
3. Pancreatitis: Using DPP-4 inhibitors, such as Linagliptin, has been associated with a small number of incidences of pancreatitis. Seek emergency medical assistance if you have severe abdominal discomfort, recurring nausea or vomiting, or an inexplicable rise in your serum lipase or amylase levels.
4. Adherence to Medication: It’s critical to take Ajaduo exactly as directed by your doctor and to follow the suggested dose regimen. The effectiveness of the drug can be impacted and the risk of problems may rise if doses are missed or exceeded.

Frequently Asked Questions (FAQs)

Ajaduo 25mg/5mg Tablet frequently asked questions include the following:

Ajaduo can be used as a first-line therapy for type 2 diabetes, according to question 1.
A: The first-line medication for type 2 diabetes is not usually ajaduo. The person’s medical history, blood sugar levels, and other aspects all play a role in the prescription decision. Your healthcare professional will choose the best course of treatment for you.

Ajaduo can induce urinary tract infections, right?
A: One of the main chemicals in Ajaduo, empagliflozin, is known to cause urinary tract infections as a side effect. It is thought to be related to an increase in the excretion of glucose in the urine. Contact your healthcare practitioner if you suffer symptoms like frequent urination, pain while urinating, or urine urgency.

3. Can Ajaduo be taken while nursing or while pregnant?
Ajaduo’s safety for use during pregnancy and breast-feeding is unknown. If you are pregnant, intend to become pregnant, or are breastfeeding, it is crucial to talk to your healthcare professional about the possible dangers and advantages.

Q4: Can I take Ajaduo along with other anti-diabetic drugs?
Ajaduo is a combo drug that already comprises Linagliptin and Empagliflozin, two anti-diabetic medications. To guarantee the suitability and safety of the combination, you should consider the usage of additional antidiabetic drugs with your healthcare professional.

Question 5: Can Ajaduo lead to hypoglycemia?
A: Ajaduo can raise the risk of hypoglycemia (low blood sugar), especially when combined with other antidiabetic drugs. Regularly checking your blood sugar levels, being aware of hypoglycemia’s warning signs and symptoms, and according to your doctor’s advice for changing medication dosages as necessary are all crucial.

Conclusion

It is typical to prescribe Ajaduo 25mg/5mg Tablet, which contains Linagliptin and Empagliflozin, for the treatment of type 2 diabetes mellitus. It functions by reducing blood sugar levels in a variety of ways. It is crucial to take the medication as directed, to take safety measures, and to notify your doctor of any side effects or concerns. Diabetes can be effectively managed by making lifestyle changes, such as eating healthily and exercising regularly, in addition to taking medication. For personalised counsel and direction tailored to your unique requirements and circumstances, always seek the opinion of a healthcare expert.