About Acera-D Capsule
Acera-D CAPSULE is a gastrointestinal medicine composed of Rabeprazole (stomach acid reducer) and Domperidone (nausea/vomiting reducer). Together they reduce the amount of acid your stomach makes and decrease the symptoms of nausea and vomiting. It treats symptoms of acid reflux due to hyperacidity, stomach ulcer (Peptic ulcer disease), and Zollinger Ellison syndrome (overproduction of acid due to a pancreatic tumour). Besides this which is used short-term to treat symptoms of gastroesophageal reflux disease (GERD).
GERD is a condition in which the sphincter (valve) located at the uppermost part of the stomach gets irritated and damaged due to excessive stomach acid production. As a result, the stomach acid and juice flow back into the food pipe, leading to stomach upset and heartburn. Heartburn is the post effect of the acid reflux with a burning like feeling that rises from the stomach towards the neck.
ACERA D CAPSULE contains two medicines, namely Rabeprazole and Domperidone. Rabeprazole is a proton pump inhibitor that helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This gastric proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum (uppermost part of the small intestine). On the other hand, Domperidone is a prokinetic agent that increases the motility of the upper gastrointestinal tract and block the vomiting inducing centre (chemoreceptor trigger zone-CTZ).
It is better to take ACERA D CAPSULE an hour before a meal or without a meal for its best results. ACERAD CAPSULE should be swallowed whole with a glass of water. Do not chew, crush, or break it. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early your symptoms may come back and your condition may worsen. An adult taking ACERAD CAPSULE might have common side effects like headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). In the case of children taking ACERA D CAPSULE might report upper respiratory tract infections (URI), headache, fever, diarrhoea, vomiting, rash, and abdominal pain. These side effects are temporary and may get resolve after some time; however if this side persists contact the doctor.
You can increase the efficacy of ACERA D CAPSULE by taking a small meal or snacks frequently. Try to avoid caffeine-containing beverages (coffee, tea), spicy/deep fried/processed foods, carbonated drinks, acidic foods like citrus fruits/vegetables (tomatoes). Tell your doctor if you have stomach or intestinal cancer, liver problem, allergic to ACERAD CAPSULE, or will have an endoscopy in the future. Prolonged intake of ACERA D CAPSULE may cause deficiency of Vitamin B-12 and low level of calcium, magnesium, and Vitamin-D leading to osteoporosis (brittle or weak bones).
Uses of Acera-D Capsule
Gastro-Esophagal Reflux Disease (GERD), Acid reflux, Heartburn, Peptic ulcer, stomach ulcers, Dyspepsia (stomach discomfort due to indigestion)
Medicinal Benefits
ACERA D CAPSULE helps in reducing the excess amount of stomach. In turn, it prevents the formation of an ulcer in the upper part of the intestine (duodenal ulcer), gastro-esophagal reflux disease (GERD) with or without ulcer and Zollinger-Ellison Syndrome in which the stomach makes exceptionally high amounts of acid. Besides ACERA D CAPSULE also treat symptoms of nausea and vomiting in adults and children more than 12 years of age (with at least 35 kg or more).
Directions for Use
Other Dosage
Storage
Side Effects of Acera-D Capsule
Every medicine has its own side effects. Likewise, ACERA D CAPSULE also has some common side effects. An adult taking ACERA D CAPSULE might have common side effects like rash, brittle bones, low vitamin B-12, loss of libido (sexual desire), cough, sore throat, runny nose, flatulence (gas formation), back pain, weakness or loss of strength, sleeplessness, headache, dizziness, and benign polyps in the stomach. These side effects are temporary and may get resolve after some time; however, if this side persists contact the doctor.
In-Depth Precautions and Warning
Drug Warnings
You should avoid taking Acera-D CAPSULE if you are allergic to ACERA D CAPSULE or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. ACERAD CAPSULE may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of ACERAD CAPSULE may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B-12, and magnesium deficiency. Intake of ACERA D CAPSULE may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor. Tell your doctor that you are using before having a specific blood test known as Chromogranin A.
Drug Interactions
Drug-Drug Interaction: ACERA D CAPSULE may interact with a blood thinner (clopidogrel, warfarin), antifungal (ketoconazole, voriconazole, itraconazole, fluconazole, posaconazole), anti-HIV drug (atazanavir, amprenavir, nelfinavir), antacid (magnesium hydroxide, aluminium hydroxide, cimetidine), iron supplements, antibiotics (clarithromycin, erythromycin, ampicillin, rifampicin), heart medicine (atropine, digoxin, amiodarone), blood pressure-lowering medicines (diltiazem), anti-cancer drug (methotrexate) and anti-nausea pills (aprepitant).
Drug-Food Interaction: ACERA D CAPSULE interact with St John’s wort plant that is used as an anti-depressant. This plant may affect the working of ACERAD CAPSULE. So avoid its intake with ACERA D CAPSULE.
Drug-Disease Interaction: ACERAD CAPSULE should be not given in patients with C. difficile induced colitis, liver disease, bone fractures, low Vitamin B12 (anaemia), low magnesium (hypomagnesemia).
