Grandem Injection (Granisetron)

Description

Grandem Injection is an antiemetic drug used to prevent nausea and vomiting caused by chemotherapy, radiation therapy as well as nausea and vomiting associated with surgeries. This medicine is not recommended for use in patients less than 2 years of age.

Side effects

Major & minor side effects for Grandem Injection
Headache
Constipation
Diarrhea
Rashes
Dizziness
Sleepiness
Irregular heartbeat
Pain at the injection site
Blurred vision
Fever

Uses of Grandem Injection

What is it prescribed for?
Chemotherapy or Radiation therapy induced nausea and vomiting
This medicine is used to prevent nausea and vomiting associated with chemotherapy or radiation therapy.
Post operative nausea and vomiting
This medicine is used to prevent nausea and vomiting associated with surgeries.

Dosage

Grandem 1 Tablet
Grandem 1mg Injection
Grandem Injection
Grandem MD Tablet

When not to use?

Allergy
This medicine is not recommended for use in patients with a known allergy to granisetron or any other inactive ingredients present in the formulation.

Warnings

Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. Your doctor may advise you to discontinue breastfeeding for a specific period of time or may prescribe an alternative medicine based on your clinical condition.
General warnings
Serotonin Syndrome
This medicine should be used with caution due to the increased risk of serotonin syndrome. This risk is especially higher in patients receiving serotogenic drugs. Report any symptoms such as dizziness, increased heart rate, changes in blood pressure, flushing, vomiting, nausea, diarrhea, etc. to the doctor immediately. Appropriate corrective measures or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Other medicines
This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.
Liver disease
This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
QT Prolongation
This medicine should be used with extreme caution in patients with prolonged QT due to the increased risk of worsening of the patient’s condition. Regular monitoring of electrolyte levels and kidney function tests are necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Dosage

Missed Dose
Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.
Overdose
Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Tramadol
Apomorphine
Formoterol
Fentanyl
Azithromycin
Selective Serotonin Reuptake inhibitors
Hydroxychloroquine
Promazine
Disease interactions
Arrhythmias
This medicine should be used with caution in patients with pre-existing arrhythmias or cardiac conduction disorders due to the increased risk of worsening of the patient’s condition. Close monitoring of heart function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Liver Disease
This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.